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JAK3 Antikörper

JAK3 Reaktivität: Human WB, ELISA, FACS, ICC Wirt: Maus Monoclonal 5H2 unconjugated
Produktnummer ABIN969224
  • Target Alle JAK3 Antikörper anzeigen
    JAK3 (Janus Kinase 3 (JAK3))
    Reaktivität
    • 83
    • 49
    • 19
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 80
    • 5
    Maus
    Klonalität
    • 71
    • 14
    Monoklonal
    Konjugat
    • 31
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser JAK3 Antikörper ist unkonjugiert
    Applikation
    • 49
    • 29
    • 16
    • 14
    • 14
    • 12
    • 9
    • 8
    • 6
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Verwendungszweck
    JAK3 Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human JAK3 expressed in E. Coli.
    Klon
    5H2
    Isotyp
    IgG1
    Top Product
    Discover our top product JAK3 Primärantikörper
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Wood, Goodman, Uckun: "Jak3 expression and genomic sequence in pediatric acute lymphoblastic leukemia." in: Leukemia & lymphoma, Vol. 43, Issue 12, pp. 2355-62, (2003) (PubMed).

  • Target
    JAK3 (Janus Kinase 3 (JAK3))
    Andere Bezeichnung
    JAK3 (JAK3 Produkte)
    Synonyme
    JAK-3 antikoerper, JAK3_HUMAN antikoerper, JAKL antikoerper, L-JAK antikoerper, LJAK antikoerper, fae antikoerper, wil antikoerper, RATJAK3 antikoerper, JAK antikoerper, Janus kinase 3 antikoerper, JAK3 antikoerper, Jak3 antikoerper
    Hintergrund

    Description: JAK3, Janus kinase 3. It is a member of the Janus kinase (JAK) family of tyrosine kinases involved in cytokine receptor-mediated intracellular signal transduction. It is predominantly expressed in immune cells and transduces a signal in response to its activation via tyrosine phosphorylation by interleukin receptors. Mutations in this gene are associated with autosomal SCID (severe combined immunodeficiency disease).

    Aliases: JAKL, LJAK

    Molekulargewicht
    125kDa
    Gen-ID
    3718
    HGNC
    3718
    UniProt
    P52333
    Pathways
    JAK-STAT Signalweg, RTK Signalweg, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus, Activated T Cell Proliferation, Unfolded Protein Response
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