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Lamin A/C Antikörper

LMNA Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 4E7 unconjugated
Produktnummer ABIN969260
  • Target Alle Lamin A/C (LMNA) Antikörper anzeigen
    Lamin A/C (LMNA)
    Reaktivität
    • 133
    • 75
    • 72
    • 27
    • 15
    • 14
    • 8
    • 7
    • 6
    • 6
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 98
    • 45
    • 2
    • 1
    Maus
    Klonalität
    • 97
    • 49
    Monoklonal
    Konjugat
    • 115
    • 9
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    Dieser Lamin A/C Antikörper ist unkonjugiert
    Applikation
    • 120
    • 54
    • 53
    • 49
    • 32
    • 31
    • 30
    • 21
    • 15
    • 7
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA
    Verwendungszweck
    LMNA Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human LMNA expressed in E. Coli.
    Klon
    4E7
    Isotyp
    IgG1
    Top Product
    Discover our top product LMNA Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Carboni, Porcu, Mura, Cocco, Marrosu, Maioli, Solla, Tranquilli, Orrù, Marrosu: "Evolution of the phenotype in a family with an LMNA gene mutation presenting with isolated cardiac involvement." in: Muscle & nerve, Vol. 41, Issue 1, pp. 85-91, (2009) (PubMed).

  • Target
    Lamin A/C (LMNA)
    Andere Bezeichnung
    LMNA (LMNA Produkte)
    Hintergrund

    Description: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Through alternate splicing, this gene encodes three type A lamin isoforms. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.

    Aliases: FPL, IDC, LFP, CDDC, EMD2, FPLD, HGPS, LDP1, LMN1, LMNC, PRO1, CDCD1, CMD1A, FPLD2, LMNL1, CMT2B1

    Molekulargewicht
    74kDa
    Gen-ID
    4000
    HGNC
    4000
    UniProt
    P02545
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, ER-Nucleus Signaling, Protein targeting to Nucleus
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