LSD1 Antikörper
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- Target Alle LSD1 (KDM1A) Antikörper anzeigen
- LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser LSD1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
- Verwendungszweck
- LSD1/AOF2 Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human LSD1 expressed in E. Coli.
- Klon
- 1B2E5
- Isotyp
- IgG1
- Top Product
- Discover our top product KDM1A Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).
: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).
: "
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Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).
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- Target
- LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
- Andere Bezeichnung
- LSD1/AOF2 (KDM1A Produkte)
- Hintergrund
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Description: The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
Aliases: KDM1, LSD1, AOF2
- Molekulargewicht
- 93kDa
- Gen-ID
- 23028
- HGNC
- 23028
- UniProt
- O60341
- Pathways
- Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effekt
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