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LSD1 Antikörper

Name: LSD1 Antikörper
Brand: antibodies-online
SKU: ABIN969264
Price: 526.71 EUR
Availability: InStock

KDM1A Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 1B2E5 unconjugated

Western blot analysis using LSD1 mouse mAb against COS (1), Hela (2), NIH/3T3 (3), A549 (4) and Jurkat (5) cell lysate. (LSD1 Antikörper)

Immunohistochemical analysis of paraffin-embedded human lung carcinoma (left) and kidney carcinoma (right), showing nuclear localization using LSD1 mouse mAb with DAB staining. (LSD1 Antikörper)

IHC

2 Abbildungen

(2 Referenzen)

Produktnummer ABIN969264

Datenblatt (PDF)

Target Alle LSD1 (KDM1A) Antikörper anzeigen

LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))
Reaktivität
81

42

35

3

3

2

1

1

1

1

1

1

1
Human
Wirt
64

15

1
Maus
Passende Sekundärantikörper
Klonalität
65

16
Monoklonal
Konjugat
55

3

3

3

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser LSD1 Antikörper ist unkonjugiert
Applikation
67

34

26

21

17

13

13

10

6

5

4

3

3

3

2

1

1
Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Verwendungszweck

LSD1/AOF2 Antibody

Aufreinigung

Ascitic fluid

Immunogen

Purified recombinant fragment of human LSD1 expressed in E. Coli.

Klon

1B2E5

Isotyp

IgG1

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anti-Lysine (K)-Specific Demethylase 1A (KDM1A) (AA 819-852) antibody
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Applikationshinweise

ELISA: 1/10000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Shi, Matson, Lan, Iwase, Baba, Shi: "Regulation of LSD1 histone demethylase activity by its associated factors." in: Molecular cell, Vol. 19, Issue 6, pp. 857-64, (2005) (PubMed).

Metzger, Wissmann, Yin, Müller, Schneider, Peters, Günther, Buettner, Schüle: "LSD1 demethylates repressive histone marks to promote androgen-receptor-dependent transcription." in: Nature, Vol. 437, Issue 7057, pp. 436-9, (2005) (PubMed).
Target

LSD1 (KDM1A) (Lysine (K)-Specific Demethylase 1A (KDM1A))

Andere Bezeichnung

LSD1/AOF2 (KDM1A Produkte)

Synonyme

AOF2 antikoerper, BHC110 antikoerper, KDM1 antikoerper, LSD1 antikoerper, 1810043O07Rik antikoerper, AA408884 antikoerper, Aof2 antikoerper, D4Ertd478e antikoerper, Kdm1 antikoerper, Lsd1 antikoerper, mKIAA0601 antikoerper, DKFZp459N2450 antikoerper, RGD1562975 antikoerper, aof2 antikoerper, kdm1 antikoerper, wu:fb82e06 antikoerper, wu:fc51a02 antikoerper, wu:fj36a05 antikoerper, wu:fj66b06 antikoerper, KDM1A antikoerper, lsd1 antikoerper, xLSD1 antikoerper, AtLSD1 antikoerper, F9F13.30 antikoerper, F9F13_30 antikoerper, LESION SIMULATING DISEASE antikoerper, LESION SIMULATING DISEASE 1 antikoerper, lysine demethylase 1A antikoerper, lysine (K)-specific demethylase 1A antikoerper, lysine (K)-specific demethylase 1a antikoerper, LSD1 zinc finger family protein antikoerper, KDM1A antikoerper, Kdm1a antikoerper, kdm1a antikoerper, LSD1 antikoerper

Hintergrund

Description: The amine oxidase domain 2 (AOF2) gene encodes a nuclear protein (LSD1, ~95 kDa) containing a Swirm domain, a FAD-binding motif, and an amine oxidase domain. This protein is a component of several histone deacetylase complexes, though it silences genes by functioning as a histone demethylase. LSD1 is a chromatin-modifying enzyme, which serve as a docking module for the stabilization of the associated corepressor complex (es) on chromatin.
Aliases: KDM1, LSD1, AOF2

Molekulargewicht

93kDa

Gen-ID

23028

HGNC

23028

UniProt

O60341

Pathways

Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Negative Regulation of intrinsic apoptotic Signaling, Warburg Effekt