MAP2K6 Antikörper

Produktnummer ABIN969269

Produktdetails anti-MAP2K6 Antikörper

Target: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MAP2K6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)

Verwendungszweck: MAP2K6 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human MAP2K6 expressed in E. Coli.

Klon: 3H12C8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-MAP2K6 Antikörper (ABIN969269)

Arning, Monté, Hansen, Wieczorek, Jagiello, Akkad, Andrich, Kraus, Saft, Epplen: "ASK1 and MAP2K6 as modifiers of age at onset in Huntington's disease." in: Journal of molecular medicine (Berlin, Germany), Vol. 86, Issue 4, pp. 485-90, (2008) (PubMed).

Details zu MAP2K6

Target: MAP2K6 (Mitogen-Activated Protein Kinase Kinase 6 (MAP2K6))

Andere Bezeichnung: MAP2K6 (MAP2K6 Produkte)

Synonyme: MAPKK6 antikoerper, MEK6 antikoerper, MKK6 antikoerper, PRKMK6 antikoerper, SAPKK-3 antikoerper, SAPKK3 antikoerper, Mkk6 antikoerper, Prkmk6 antikoerper, MKK3 antikoerper, map2k3 antikoerper, zMKK3 antikoerper, map2k6 antikoerper, mitogen-activated protein kinase kinase 6 antikoerper, mitogen-activated protein kinase kinase 6 L homeolog antikoerper, MAP2K6 antikoerper, Map2k6 antikoerper, map2k6 antikoerper, map2k6.L antikoerper

Hintergrund:

Description: This gene encodes a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress induced cell cycle arrest, transcription activation and apoptosis. Tissue specificity: Isoform 2 is only expressed in skeletal muscle. Isoform 1, on the other hand, is found in skeletal muscle, heart, and in lesser extent in liver or pancreas .

Aliases: MEK6, MKK6, MAPKK6, PRKMK6, SAPKK3, MAP2K6

Molekulargewicht: 38kDa

Gen-ID: 5608

HGNC: 5608

UniProt: P52564

Pathways: MAPK Signalweg, TLR Signalweg, Activation of Innate immune Response, Regulation of Muscle Cell Differentiation, Toll-Like Receptors Cascades