MSH6 Antikörper
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- Target Alle MSH6 Antikörper anzeigen
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser MSH6 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC), Flow Cytometry (FACS)
- Verwendungszweck
- MSH6 Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human MSH6 expressed in E. Coli.
- Klon
- 3E1
- Isotyp
- IgG2a
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Germ-line mutations in mismatch repair genes associated with prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 9, pp. 2460-7, (2009) (PubMed).
: "
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Germ-line mutations in mismatch repair genes associated with prostate cancer." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 18, Issue 9, pp. 2460-7, (2009) (PubMed).
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- Target
- MSH6 (MutS Homolog 6 (E. Coli) (MSH6))
- Andere Bezeichnung
- MSH6 (MSH6 Produkte)
- Synonyme
- GTBP antikoerper, GTMBP antikoerper, HNPCC5 antikoerper, HSAP antikoerper, p160 antikoerper, cb326 antikoerper, wu:fb36c12 antikoerper, LOC100227810 antikoerper, AU044881 antikoerper, AW550279 antikoerper, Gtmbp antikoerper, mutS homolog 6 antikoerper, mutS homolog 6 (E. coli) antikoerper, DNA mismatch repair protein antikoerper, MSH6 antikoerper, msh6 antikoerper, Msh6 antikoerper
- Hintergrund
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Description: This gene encodes a protein similar to the MutS protein. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides, prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer.
Aliases: GTBP, HSAP, HNPCC5
- Molekulargewicht
- 160kDa
- Gen-ID
- 2956
- HGNC
- 2956
- UniProt
- P52701
- Pathways
- DNA Reparatur, Chromatin Binding, Production of Molecular Mediator of Immune Response
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