MSI2 Antikörper

Produktnummer ABIN969295

Produktdetails anti-MSI2 Antikörper

Target: MSI2 (Musashi Homolog 2 (MSI2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MSI2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human MSI2 expressed in E. coli.

Klon: 2C11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-MSI2 Antikörper (ABIN969295)

Talmud, Drenos, Shah, Shah, Palmen, Verzilli, Gaunt, Pallas, Lovering, Li, Casas, Sofat, Kumari, Rodriguez, Johnson, Newhouse, Dominiczak, Samani, Caulfield, Sever, Stanton, Shields, Padmanabhan et al.: "Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. ..." in: American journal of human genetics, Vol. 85, Issue 5, pp. 628-42, (2009) (PubMed).

De Weer, Speleman, Cauwelier, Van Roy, Yigit, Verhasselt, De Moerloose, Benoit, Noens, Selleslag, Lippert, Struski, Bastard, De Paepe, Vandenberghe, Hagemeijer, Dastugue, Poppe: "EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22." in: Haematologica, Vol. 93, Issue 12, pp. 1903-7, (2008) (PubMed).

Details zu MSI2

Target: MSI2 (Musashi Homolog 2 (MSI2))

Andere Bezeichnung: MSI2 (MSI2 Produkte)

Synonyme: MSI2H antikoerper, 1700105C15Rik antikoerper, AI451722 antikoerper, AI563628 antikoerper, AW489193 antikoerper, Msi2h antikoerper, RGD1560397 antikoerper, MSI2 antikoerper, musashi-2 antikoerper, musashi2 antikoerper, xrp1 antikoerper, msi2 antikoerper, zgc:174035 antikoerper, zgc:63812 antikoerper, cb746 antikoerper, fi47b09 antikoerper, wu:fb02d08 antikoerper, wu:fi32d12 antikoerper, wu:fi47b09 antikoerper, musashi RNA binding protein 2 antikoerper, musashi RNA-binding protein 2 antikoerper, musashi RNA binding protein 2 S homeolog antikoerper, musashi RNA-binding protein 2b antikoerper, musashi RNA-binding protein 2a antikoerper, MSI2 antikoerper, Msi2 antikoerper, msi2.S antikoerper, msi2 antikoerper, msi2b antikoerper, msi2a antikoerper

Hintergrund:

Description: Msi2 (musashi homolog 2), also known as MSI2H, is a 328 amino acid protein that localizes to the cytoplasm and contains two RRM (RNA recognition motif) domains. Expressed ubiquitously at low levels, Msi2 functions as an RNA binding protein that, by regulating the expression of target mRNAs, is thought to play a role in the proliferation and maintenance of stem cells within the central nervous system. Msi2 is subject to posttranslational phosphorylation and is upregulated in response to brain injury, suggesting a role in healing and brain tissue regeneration. Chromosomal aberrations involving the Msi2 gene are associated with the progression of chronic myeloid leukemia. Multiple isoforms of Msi2 exist due to alternative splicing events.Tissue specificity: Ubiquitous, detected at low levels.

Aliases: MSI2H, MGC3245, FLJ36569, MSI2

Molekulargewicht: 35 kDa

Gen-ID: 124540

HGNC: 124540