CD73 Antikörper
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- Target Alle CD73 (NT5E) Antikörper anzeigen
- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD73 Antikörper ist unkonjugiert
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Applikation
- Immunohistochemistry (IHC), ELISA
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of NT5E expressed in E. coli.
- Klon
- 1D7
- Isotyp
- IgG1
- Top Product
- Discover our top product NT5E Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, IHC: 1:200 - 1:1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo." in: Oncology reports, Vol. 17, Issue 6, pp. 1341-6, (2007) (PubMed).
: "Extracellular adenine nucleotides metabolism in astrocyte cultures from different brain regions." in: Neurochemistry international, Vol. 43, Issue 7, pp. 621-8, (2003) (PubMed).
: "
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Effects of ecto-5'-nucleotidase on human breast cancer cell growth in vitro and in vivo." in: Oncology reports, Vol. 17, Issue 6, pp. 1341-6, (2007) (PubMed).
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- Target
- CD73 (NT5E) (5'-Nucleotidase, Ecto (CD73) (NT5E))
- Andere Bezeichnung
- NT5E (NT5E Produkte)
- Synonyme
- CALJA antikoerper, CD73 antikoerper, E5NT antikoerper, NT antikoerper, NT5 antikoerper, NTE antikoerper, eN antikoerper, eNT antikoerper, zgc:63784 antikoerper, NT5E antikoerper, MGC114869 antikoerper, PSPTO2277 antikoerper, 2210401F01Rik antikoerper, AI447961 antikoerper, Nt5 antikoerper, 5'-nucleotidase ecto antikoerper, 5'-nucleotidase, ecto (CD73) antikoerper, 5'-nucleotidase antikoerper, 5' nucleotidase, ecto antikoerper, NT5E antikoerper, nt5e antikoerper, nt5e.S antikoerper, PSPTO_2277 antikoerper, CBU_1233 antikoerper, MCA1322 antikoerper, Nt5e antikoerper
- Hintergrund
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Description: 5'-nucleotidase, ecto (NT5E), also known as CD73 (Cluster of Differentiation 73). Ecto-5-prime-nucleotidase (5-prime-ribonucleotide phosphohydrolase, EC 3.1.3.5) catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP. The enzyme consists of a dimer of 2 identical 70-kD subunits bound by a glycosyl phosphatidyl inositol linkage to the external face of the plasma membrane. The enzyme is used as a marker of lymphocyte differentiation. Consequently, a deficiency of NT5 occurs in a variety of immunodeficiency diseases (e.g., see MIM 102700, MIM 300300). Other forms of 5-prime nucleotidase exist in the cytoplasm and lysosomes and can be distinguished from ecto-NT5 by their substrate affinities, requirement for divalent magnesium ion, activation by ATP, and inhibition by inorganic phosphate.
Aliases: eN, NT5, CD73
- Molekulargewicht
- 70 kDa
- Gen-ID
- 4907
- HGNC
- 4907
- Pathways
- Synaptic Membrane, Ribonucleoside Biosynthetic Process
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