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PARL Antikörper (AA 112-167)

PARL Reaktivität: Human ELISA Wirt: Maus Monoclonal 8C4B2 unconjugated
Produktnummer ABIN969340
  • Target Alle PARL Antikörper anzeigen
    PARL (Presenilin Associated, Rhomboid-Like (PARL))
    Bindungsspezifität
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 112-167
    Reaktivität
    • 21
    • 10
    • 9
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 18
    • 2
    • 2
    Maus
    Klonalität
    • 20
    • 2
    Monoklonal
    Konjugat
    • 15
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PARL Antikörper ist unkonjugiert
    Applikation
    • 12
    • 8
    • 8
    • 2
    • 2
    • 1
    • 1
    • 1
    ELISA
    Verwendungszweck
    PARL Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of PARL (aa112-167) expressed in E. Coli.
    Klon
    8C4B2
    Isotyp
    IgG2b
    Top Product
    Discover our top product PARL Primärantikörper
  • Applikationshinweise
    ELISA: 1/10000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • McQuibban, Saurya, Freeman: "Mitochondrial membrane remodelling regulated by a conserved rhomboid protease." in: Nature, Vol. 423, Issue 6939, pp. 537-41, (2003) (PubMed).

    Pellegrini, Passer, Canelles, Lefterov, Ganjei, Fowlkes, Koonin, DAdamio: "PAMP and PARL, two novel putative metalloproteases interacting with the COOH-terminus of Presenilin-1 and -2." in: Journal of Alzheimer's disease : JAD, Vol. 3, Issue 2, pp. 181-190, (2002) (PubMed).

  • Target
    PARL (Presenilin Associated, Rhomboid-Like (PARL))
    Andere Bezeichnung
    PARL (PARL Produkte)
    Synonyme
    PSARL antikoerper, PSARL1 antikoerper, PSENIP2 antikoerper, RHBDS1 antikoerper, D16Ertd607e antikoerper, PRO2207 antikoerper, Psarl antikoerper, parl antikoerper, zgc:112986 antikoerper, presenilin associated rhomboid like antikoerper, presenilin associated, rhomboid-like antikoerper, presenilin associated, rhomboid-like a antikoerper, PARL antikoerper, Parl antikoerper, parla antikoerper
    Hintergrund

    Description: PARL: presenilin associated, rhomboid-like. This gene encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. This gene may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Aliases: PSARL, PSARL1, RHBDS1

    Gen-ID
    55486
    HGNC
    55486
    UniProt
    Q9H300
    Pathways
    Autophagie
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