PEG10 Antikörper (AA 1-120)

Produktnummer ABIN969348

Produktdetails anti-PEG10 Antikörper

Target: PEG10 (Paternally Expressed 10 (PEG10))

Bindungsspezifität: AA 1-120

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PEG10 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)

Verwendungszweck: PEG10 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of PEG10 (aa1-120) expressed in E. Coli.

Klon: 1B1C4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-PEG10 Antikörper (ABIN969348)

Kochetov, Ahmad, Ivanisenko, Volkova, Kolchanov, Sarai: "uORFs, reinitiation and alternative translation start sites in human mRNAs." in: FEBS letters, Vol. 582, Issue 9, pp. 1293-7, (2008) (PubMed).

Wang, Xiao, Hu, Chen, Liu, Hu: "PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma." in: FEBS letters, Vol. 582, Issue 18, pp. 2793-8, (2008) (PubMed).

Jie, Lang, Jian, Chaoqun, Dehua, Yi, Yanping, Luokun, Qiuping, Hui, Feili, Boquan, Youxin, Jinquan: "Androgen activates PEG10 to promote carcinogenesis in hepatic cancer cells." in: Oncogene, Vol. 26, Issue 39, pp. 5741-51, (2007) (PubMed).

Details zu PEG10

Target: PEG10 (Paternally Expressed 10 (PEG10))

Andere Bezeichnung: PEG10 (PEG10 Produkte)

Synonyme: EDR antikoerper, HB-1 antikoerper, MEF3L antikoerper, Mar2 antikoerper, Mart2 antikoerper, RGAG3 antikoerper, AA407948 antikoerper, Edr antikoerper, MyEF-3 antikoerper, paternally expressed 10 antikoerper, PEG10 antikoerper, Peg10 antikoerper

Hintergrund:

Description: PEG10: paternally expressed 10. This gene includes two overlapping reading frames of the same transcript encoding distinct isoforms. The shorter isoform has a CCHC-type zinc finger motif containing a sequence characteristic of gag proteins of most retroviruses and some retrotransposons, and it functions in part by interacting with members of the TGF-beta receptor family. The longer isoform has the active-site DSG consensus sequence of the protease domain of pol proteins. The longer isoform is the result of -1 translational frameshifting that is also seen in some retroviruses. Expression of these two isoforms only comes from the paternal allele due to imprinting. Increased gene expression (as observed by an increase in mRNA levels) is associated with hepatocellular carcinomas.

Aliases: Edr, HB-1, Mar2, MEF3L, Mart2, RGAG3, KIAA1051

Gen-ID: 23089

HGNC: 23089

UniProt: Q86TG7