PGA5 Antikörper

Produktnummer ABIN969350

Produktdetails anti-PGA5 Antikörper

Target: PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PGA5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PGA5 expressed in E. coli.

Klon: 2C1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Details zu PGA5

Target: PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))

Andere Bezeichnung: PGA5 (PGA5 Produkte)

Synonyme: PGA3 antikoerper, PGA4 antikoerper, 1110035E17Rik antikoerper, Pepf antikoerper, pepsinogen 5, group I (pepsinogen A) antikoerper, pepsinogen 5, group I antikoerper, PGA5 antikoerper, Pga5 antikoerper

Hintergrund:

Description: PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity ( pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.

Aliases: Pepsinogen 5, Pepsin A

Molekulargewicht: 42 kDa

Gen-ID: 5222

HGNC: 5222