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PGA5 Antikörper

PGA5 Reaktivität: Human WB, ELISA, IHC Wirt: Maus Monoclonal 2C1 unconjugated
Produktnummer ABIN969350
  • Target Alle PGA5 Antikörper anzeigen
    PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))
    Reaktivität
    • 24
    • 1
    • 1
    Human
    Wirt
    • 20
    • 4
    Maus
    Klonalität
    • 21
    • 3
    Monoklonal
    Konjugat
    • 12
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PGA5 Antikörper ist unkonjugiert
    Applikation
    • 17
    • 11
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human PGA5 expressed in E. coli.
    Klon
    2C1
    Isotyp
    IgG1
    Top Product
    Discover our top product PGA5 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Target
    PGA5 (Pepsinogen 5, Group I (Pepsinogen A) (PGA5))
    Andere Bezeichnung
    PGA5 (PGA5 Produkte)
    Synonyme
    PGA3 antikoerper, PGA4 antikoerper, 1110035E17Rik antikoerper, Pepf antikoerper, pepsinogen 5, group I (pepsinogen A) antikoerper, pepsinogen 5, group I antikoerper, PGA5 antikoerper, Pga5 antikoerper
    Hintergrund

    Description: PGA5: Pepsinogen 5, group I (pepsinogen A). Pepsinogens are the inactive precursors of pepsin, the major acid protease found in the stomach. Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. Pepsin consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, is necessary to convert the inactive enzyme and to maintain the optimum acidity ( pH 1-3) for pepsin function. Pepsin is particularly effective in cleaving peptide bonds involving aromatic amino acids. Pepsin shows extremely broad specificity, although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent. PGA5 is a member of the subfamily A1 within the pepsin family and is the predominant endopeptidase in the gastric juice of vertebrates. PGA5 is inhibited by ovUS-1, a uterine serpin.

    Aliases: Pepsinogen 5, Pepsin A

    Molekulargewicht
    42 kDa
    Gen-ID
    5222
    HGNC
    5222
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