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Prohibitin Antikörper

PHB Reaktivität: Human WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 5H7 unconjugated
Produktnummer ABIN969353
  • Target Alle Prohibitin (PHB) Antikörper anzeigen
    Prohibitin (PHB)
    Reaktivität
    • 132
    • 61
    • 58
    • 11
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 112
    • 20
    Maus
    Klonalität
    • 104
    • 28
    Monoklonal
    Konjugat
    • 65
    • 12
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Prohibitin Antikörper ist unkonjugiert
    Applikation
    • 100
    • 49
    • 46
    • 24
    • 20
    • 18
    • 14
    • 13
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Verwendungszweck
    PHB Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human PHB expressed in E. Coli.
    Klon
    5H7
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shi, Li, Liu, Xu, Tang, Liang, Zhao, Yang: "Nuclear matrix protein, prohibitin, was down-regulated and translocated from nucleus to cytoplasm during the differentiation of osteosarcoma MG-63 cells induced by ginsenoside Rg1, cinnamic acid, and tanshinone IIA (RCT)." in: Journal of cellular biochemistry, Vol. 108, Issue 4, pp. 926-34, (2009) (PubMed).

    Ande, Mishra: "Prohibitin interacts with phosphatidylinositol 3,4,5-triphosphate (PIP3) and modulates insulin signaling." in: Biochemical and biophysical research communications, Vol. 390, Issue 3, pp. 1023-8, (2009) (PubMed).

  • Target
    Prohibitin (PHB)
    Andere Bezeichnung
    PHB (PHB Produkte)
    Synonyme
    phb1 antikoerper, MGC75944 antikoerper, PHB antikoerper, Phb antikoerper, ACYPI000080 antikoerper, phb antikoerper, PHB1 antikoerper, Bap32 antikoerper, sr:nyz128 antikoerper, wu:fa18f07 antikoerper, wu:fb09f05 antikoerper, prohibitin1 antikoerper, xphb1 antikoerper, prohibitin antikoerper, prohibitin-2 antikoerper, prohibitin L homeolog antikoerper, PHB antikoerper, phb antikoerper, LOC484431 antikoerper, LOC5576054 antikoerper, Phb antikoerper, phb.L antikoerper
    Hintergrund

    Description: Prohibitin is an evolutionarily conserved gene that is ubiquitously expressed. It is thought to be a negative regulator of cell proliferation and may be a tumor suppressor. Mutations in PHB have been linked to sporadic breast cancer. Prohibitin is expressed as two transcripts with varying lengths of 3' untranslated region. The longer transcript is present at higher levels in proliferating tissues and cells, suggesting that this longer 3' untranslated region may function as a trans-acting regulatory RNA.

    Aliases: PHB1

    Molekulargewicht
    30kDa
    Gen-ID
    5245
    HGNC
    5245
    UniProt
    P35232
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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