PPP1CA Antikörper

Produktnummer ABIN969359

Produktdetails anti-PPP1CA Antikörper

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PPP1CA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Aufreinigung: purified

Immunogen: Purified recombinant fragment of human PPP1A expressed in E. coli.

Klon: 6D1

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1:10000, WB: 1:500 - 1:2000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: 4°C, -20°C for long term storage

Referenzen für anti-PPP1CA Antikörper (ABIN969359)

Luo, Peterson, Garcia, Coombs, Kofahl, Heinrich, Shabanowitz, Hunt, Yost, Virshup: "Protein phosphatase 1 regulates assembly and function of the beta-catenin degradation complex." in: The EMBO journal, Vol. 26, Issue 6, pp. 1511-21, (2007) (PubMed).

Eto, Kirkbride, Elliott, Lo, Brautigan: "Association of the tensin N-terminal protein-tyrosine phosphatase domain with the alpha isoform of protein phosphatase-1 in focal adhesions." in: The Journal of biological chemistry, Vol. 282, Issue 24, pp. 17806-15, (2007) (PubMed).

Details zu PPP1CA

Target: PPP1CA (Protein Phosphatase 1, Catalytic Subunit, alpha Isoform (PPP1CA))

Andere Bezeichnung: PPP1A (PPP1CA Produkte)

Synonyme: PP-1A antikoerper, PP1A antikoerper, PP1alpha antikoerper, PPP1A antikoerper, Ppp1c antikoerper, dism2 antikoerper, ppp1a antikoerper, wu:fc04c08 antikoerper, wu:fc09b07 antikoerper, wu:fc30g11 antikoerper, wu:fe05h08 antikoerper, zgc:85729 antikoerper, Ppp1ca antikoerper, fb18b03 antikoerper, fd20h04 antikoerper, wu:fb18b03 antikoerper, wu:fd20h04 antikoerper, wu:fl22a03 antikoerper, zgc:55744 antikoerper, zgc:76940 antikoerper, protein phosphatase 1 catalytic subunit alpha antikoerper, protein phosphatase 1, catalytic subunit, alpha isoform antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme L homeolog antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme a antikoerper, protein phosphatase 1, catalytic subunit, alpha isozyme b antikoerper, PPP1CA antikoerper, Ppp1ca antikoerper, ppp1ca.L antikoerper, ppp1ca antikoerper, ppp1caa antikoerper, ppp1cab antikoerper

Hintergrund:

Description: The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Aliases: PP-1A, PPP1A, MGC1674, MGC15877, PP1alpha, PPP1CA

Molekulargewicht: 38 kDa

Gen-ID: 5499

HGNC: 5499

Pathways: M Phase, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process, Lipid Metabolism