PRKAA1 Antikörper

Produktnummer ABIN969364

Produktdetails anti-PRKAA1 Antikörper

Target: PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRKAA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)

Verwendungszweck: PRKAA1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human PRKAA1 expressed in E. Coli.

Klon: 2B7

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-PRKAA1 Antikörper (ABIN969364)

Pan, Yang, Cao, Song, Wallin, Kivlin, Lu, Hu, Di, Wan: "AMPK mediates curcumin-induced cell death in CaOV3 ovarian cancer cells." in: Oncology reports, Vol. 20, Issue 6, pp. 1553-9, (2008) (PubMed).

Egawa, Kamata, Kushiyama, Sakoda, Fujishiro, Horike, Yoneda, Nakatsu, Ying, Jun, Tsuchiya, Takata, Kurihara, Asano: "Long-term forskolin stimulation induces AMPK activation and thereby enhances tight junction formation in human placental trophoblast BeWo cells." in: Placenta, Vol. 29, Issue 12, pp. 1003-8, (2008) (PubMed).

Details zu PRKAA1

Target: PRKAA1 (Protein Kinase, AMP-Activated, alpha 1 Catalytic Subunit (PRKAA1))

Andere Bezeichnung: PRKAA1 (PRKAA1 Produkte)

Synonyme: AMPK antikoerper, AMPKa1 antikoerper, cb116 antikoerper, im:7154392 antikoerper, sb:cb130 antikoerper, wu:fa94c10 antikoerper, AMPK1 antikoerper, AMPKalpha1 antikoerper, AI194361 antikoerper, AI450832 antikoerper, AL024255 antikoerper, C130083N04Rik antikoerper, ampk antikoerper, ampka1 antikoerper, PRKAA1 antikoerper, protein kinase AMP-activated catalytic subunit alpha 1 antikoerper, protein kinase, AMP-activated, alpha 1 catalytic subunit antikoerper, protein kinase, AMP-activated, alpha 1 catalytic subunit L homeolog antikoerper, PRKAA1 antikoerper, prkaa1 antikoerper, Prkaa1 antikoerper, prkaa1.L antikoerper

Hintergrund:

Description: The protein belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Aliases: AMPK, AMPKa1, MGC33776, MGC57364, PRKAA1

Molekulargewicht: 64kDa

Gen-ID: 5562

HGNC: 5562

UniProt: Q13131

Pathways: AMPK Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effekt