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PSIP1 Antikörper

PSIP1 Reaktivität: Human WB, IHC, ELISA, ICC Wirt: Maus Monoclonal 6E4 unconjugated
Produktnummer ABIN969370
  • Target Alle PSIP1 Antikörper anzeigen
    PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))
    Reaktivität
    • 27
    • 17
    • 11
    • 11
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 5
    • 3
    Human
    Wirt
    • 16
    • 14
    Maus
    Klonalität
    • 16
    • 14
    Monoklonal
    Konjugat
    • 23
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PSIP1 Antikörper ist unkonjugiert
    Applikation
    • 20
    • 9
    • 8
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    Verwendungszweck
    PSIP1 Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human PSIP1 expressed in E. Coli.
    Klon
    6E4
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Shun, Botbol, Li, Di Nunzio, Daigle, Yan, Lieberman, Lavigne, Engelman: "Identification and characterization of PWWP domain residues critical for LEDGF/p75 chromatin binding and human immunodeficiency virus type 1 infectivity." in: Journal of virology, Vol. 82, Issue 23, pp. 11555-67, (2008) (PubMed).

  • Target
    PSIP1 (PC4 and SFRS1 Interacting Protein 1 (PSIP1))
    Andere Bezeichnung
    PSIP1 (PSIP1 Produkte)
    Synonyme
    PSIP1 antikoerper, im:7149861 antikoerper, zgc:109898 antikoerper, LEDGF antikoerper, p75 antikoerper, PSIP2 antikoerper, DFS70 antikoerper, PAIP antikoerper, p52 antikoerper, AA408851 antikoerper, AU015605 antikoerper, Dfs70 antikoerper, Ledgfa antikoerper, Ledgfb antikoerper, Psip2 antikoerper, Ledgf antikoerper, SBP75 antikoerper, LEDGF/p75 antikoerper, PC4 and SFRS1 interacting protein 1 S homeolog antikoerper, PC4 and SFRS1 interacting protein 1 antikoerper, PC4 and SFRS1 interacting protein 1a antikoerper, LEDGF/p75 transcription factor-like antikoerper, psip1.S antikoerper, PSIP1 antikoerper, psip1a antikoerper, psip1 antikoerper, Psip1 antikoerper
    Hintergrund

    Description: Transcriptional coactivator involved in neuroepithelial stem cell differentiation and neurogenesis. Involved in particular in lens epithelial cell gene regulation and stress responses. May play an important role in lens epithelial to fiber cell terminal differentiation. May play a protective role during stress-induced apoptosis. Isoform 2 is a more general and stronger transcriptional coactivator. Isoform 2 may also act as an adapter to coordinate pre-mRNA splicing. Cellular cofactor for lentiviral integration. Tissue specificity: Widely expressed. Expressed at high level in the thymus. Expressed in fetal and adult brain. Expressed in neurons, but not astrocytes. Markedly elevated in fetal as compared to adult brain. In the adult brain, expressed in the subventricular zone (SVZ), in hippocampus, and undetectable elsewhere. In the fetal brain, expressed in the germinal neuroepithelium and cortical plate regions.

    Aliases: p52, p75, PAIP, DFS70, LEDGF, PSIP2, MGC74712, PSIP1

    Molekulargewicht
    75kDa
    Gen-ID
    11168
    HGNC
    11168
    UniProt
    O75475
    Pathways
    Chromatin Binding, Ribonucleoprotein Complex Subunit Organization
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