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PTH1R Antikörper

PTH1R Reaktivität: Human WB, IHC, ELISA, ICC Wirt: Maus Monoclonal 4D2 unconjugated
Produktnummer ABIN969372
  • Target Alle PTH1R Antikörper anzeigen
    PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
    Reaktivität
    • 42
    • 17
    • 12
    • 8
    • 8
    • 6
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 35
    • 6
    • 1
    Maus
    Klonalität
    • 36
    • 6
    Monoklonal
    Konjugat
    • 31
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PTH1R Antikörper ist unkonjugiert
    Applikation
    • 28
    • 18
    • 15
    • 10
    • 7
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human PTH1R expressed in E. coli.
    Klon
    4D2
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Dean, Vilardaga, Potts, Gardella: "Altered selectivity of parathyroid hormone (PTH) and PTH-related protein (PTHrP) for distinct conformations of the PTH/PTHrP receptor." in: Molecular endocrinology (Baltimore, Md.), Vol. 22, Issue 1, pp. 156-66, (2007) (PubMed).

    Yang, Hoang, Kubo, Kawano, Chou, Sowers, Huvos, Meyers, Healey, Gorlick: "Over-expression of parathyroid hormone Type 1 receptor confers an aggressive phenotype in osteosarcoma." in: International journal of cancer. Journal international du cancer, Vol. 121, Issue 5, pp. 943-54, (2007) (PubMed).

  • Target
    PTH1R (Parathyroid Hormone 1 Receptor (PTH1R))
    Andere Bezeichnung
    PTH1R (PTH1R Produkte)
    Synonyme
    PFE antikoerper, PTHR antikoerper, PTHR1 antikoerper, PPR antikoerper, Pthr antikoerper, Pthr1 antikoerper, pthr1 antikoerper, zPTH1R antikoerper, PTHrel antikoerper, PTH1 antikoerper, PTH antikoerper, parathyroid hormone 1 receptor antikoerper, parathyroid hormone 1 receptor a antikoerper, PTH1R antikoerper, Pth1r antikoerper, pth1ra antikoerper
    Hintergrund

    Description: The protein encoded by this gene is a member of the G-protein coupled receptor family 2. This protein is a receptor for parathyroid hormone (PTH) and for parathyroid hormone-like hormone (PTHLH). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase and also a phosphatidylinositol-calcium second messenger system. Defects in this receptor are known to be the cause of Jansen's metaphyseal chondrodysplasia (JMC), chondrodysplasia Blomstrand type (BOCD), as well as enchodromatosis. Two transcript variants encoding the same protein have been found for this gene.

    Aliases: PFE, PTHR, PTHR1, MGC138426, MGC138452, PTH1R

    Molekulargewicht
    66 kDa
    Gen-ID
    5745
    HGNC
    5745
    Pathways
    Regulation of Carbohydrate Metabolic Process
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