RUNX1 Antikörper
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- Target Alle RUNX1 Antikörper anzeigen
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser RUNX1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Verwendungszweck
- RUNX1 Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Synthesized peptide of human RUNX1.
- Klon
- 2B5
- Isotyp
- IgG1
- Top Product
- Discover our top product RUNX1 Primärantikörper
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis." in: Journal of virology, Vol. 82, Issue 13, pp. 6395-408, (2008) (PubMed).
: "AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4402-8, (2008) (PubMed).
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RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis." in: Journal of virology, Vol. 82, Issue 13, pp. 6395-408, (2008) (PubMed).
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- Target
- RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))
- Andere Bezeichnung
- RUNX1 (RUNX1 Produkte)
- Hintergrund
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Description: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.
Aliases: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1, RUNX1
- Molekulargewicht
- 55kDa
- Gen-ID
- 861
- HGNC
- 861
- UniProt
- Q01196
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