RUNX1 Antikörper

Produktnummer ABIN969390

Produktdetails anti-RUNX1 Antikörper

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser RUNX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: RUNX1 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Synthesized peptide of human RUNX1.

Klon: 2B5

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-RUNX1 Antikörper (ABIN969390)

Marshall, Moore, Ohki, Kitabayashi, Patterson, Ornelles: "RUNX1 permits E4orf6-directed nuclear localization of the adenovirus E1B-55K protein and associates with centers of viral DNA and RNA synthesis." in: Journal of virology, Vol. 82, Issue 13, pp. 6395-408, (2008) (PubMed).

Ichikawa, Goyama, Asai, Kawazu, Nakagawa, Takeshita, Chiba, Ogawa, Kurokawa: "AML1/Runx1 negatively regulates quiescent hematopoietic stem cells in adult hematopoiesis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 7, pp. 4402-8, (2008) (PubMed).

Details zu RUNX1

Target: RUNX1 (Runt-Related Transcription Factor 1 (RUNX1))

Andere Bezeichnung: RUNX1 (RUNX1 Produkte)

Synonyme: RUNX1 antikoerper, runx1 antikoerper, AI462102 antikoerper, AML1 antikoerper, Cbfa2 antikoerper, Pebp2a2 antikoerper, Pebpa2b antikoerper, AML1-EVI-1 antikoerper, AMLCR1 antikoerper, CBFA2 antikoerper, EVI-1 antikoerper, PEBP2aB antikoerper, runxa antikoerper, Runx-1 antikoerper, XAML antikoerper, Xaml1 antikoerper, aml antikoerper, aml-1 antikoerper, aml1 antikoerper, aml1-evi-1 antikoerper, amlcr1 antikoerper, cbfa2 antikoerper, evi-1 antikoerper, pebp2ab antikoerper, Aml1 antikoerper, uncharacterized LOC473981 antikoerper, runt-related transcription factor antikoerper, runt related transcription factor 1 antikoerper, runt-related transcription factor 1 antikoerper, runt related transcription factor 1 L homeolog antikoerper, LOC473981 antikoerper, runt antikoerper, Runx1 antikoerper, RUNX1 antikoerper, runx1 antikoerper, runx1.L antikoerper

Hintergrund:

Description: Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq) Tissue specificity: Expressed in all tissues examined except brain and heart. Highest levels in thymus, bone marrow and peripheral blood.

Aliases: AML1, CBFA2, EVI-1, AMLCR1, PEBP2aB, AML1-EVI-1, RUNX1

Molekulargewicht: 55kDa

Gen-ID: 861

HGNC: 861

UniProt: Q01196