SMAD5 Antikörper

Produktnummer ABIN969404

Produktdetails anti-SMAD5 Antikörper

Target: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser SMAD5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Verwendungszweck: SMAD5 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human SMAD5 expressed in E. Coli.

Klon: 3H9

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-SMAD5 Antikörper (ABIN969404)

Chang, Chang, Lee, Lee, Yeh, Yeh, Cheng, Chien, Chiu: "Tumor cell cycle arrest induced by shear stress: Roles of integrins and Smad." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, Issue 10, pp. 3927-32, (2008) (PubMed).

Monzen, Ito, Naito, Kasai, Hiroi, Hayashi, Shiojima, Yamazaki, Miyazono, Asashima, Nagai, Komuro: "A crucial role of a high mobility group protein HMGA2 in cardiogenesis." in: Nature cell biology, Vol. 10, Issue 5, pp. 567-74, (2008) (PubMed).

Details zu SMAD5

Target: SMAD5 (SMAD, Mothers Against DPP Homolog 5 (SMAD5))

Andere Bezeichnung: SMAD5 (SMAD5 Produkte)

Synonyme: DWFC antikoerper, JV5-1 antikoerper, MADH5 antikoerper, Madh5 antikoerper, SBN antikoerper, fb67b04 antikoerper, mad antikoerper, madh5 antikoerper, sb:cb400 antikoerper, smd5 antikoerper, wu:fb67b04 antikoerper, SMAD5 antikoerper, DKFZp468M0619 antikoerper, 1110051M15Rik antikoerper, AI451355 antikoerper, Dwf-C antikoerper, MusMLP antikoerper, SMAD family member 5 antikoerper, SMAD5 antikoerper, Smad5 antikoerper, smad5 antikoerper

Hintergrund:

Description: Transcriptional modulator activated by BMP (bone morphogenetic proteins) type 1 receptor kinase. SMAD5 is a receptor-regulated SMAD (R-SMAD). SMAD5 is required for normal development of the cardiovascular system in vivo, lack of the SMAD5 gene results in apoptosis of cardiac myocytes. 3 Upregulation of SMAD5 has been reported to mediate apoptosis of gastric epithelial cells induced by Helicobacter pylori infection. Tissue specificity: Ubiquitous.

Aliases: Dwfc, JV5-1, MADH5, DKFZp781C1895, DKFZp781O1323, SMAD5

Molekulargewicht: 52kDa

Gen-ID: 4090

HGNC: 4090

UniProt: Q99717