SNAIL Antikörper
(2 Referenzen)-
- Target Alle SNAIL (SNAI1) Antikörper anzeigen
- SNAIL (SNAI1)
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser SNAIL Antikörper ist unkonjugiert
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Applikation
- ELISA
- Verwendungszweck
- SNAI1 Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human SNAI1 expressed in E. Coli.
- Klon
- 6D2
- Isotyp
- IgG1
- Top Product
- Discover our top product SNAI1 Primärantikörper
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anti-SNAIL (SNAI1) (C-Term) antibody
SNAI1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-SNAIL (SNAI1) (AA 1-100) antibodySNAI1 Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-SNAIL (SNAI1) (AA 9-39), (N-Term) antibodySNAI1 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB01400 unconjugated
anti-SNAIL (SNAI1) (C-Term) antibodySNAI1 Reaktivität: Human, Maus, Ratte WB, ELISA, IHC, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-SNAIL (SNAI1) (N-Term) antibodySNAI1 Reaktivität: Human, Maus, Ratte, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-SNAIL (SNAI1) (AA 121-230) antibodySNAI1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2G11 unconjugated
anti-SNAIL (SNAI1) (AA 1-264) antibodySNAI1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-SNAIL (SNAI1) antibodySNAI1 Reaktivität: Human, Maus, Ratte IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-SNAIL (SNAI1) antibodySNAI1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-SNAIL (SNAI1) antibodySNAI1 Reaktivität: Human WB, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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: "Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression." in: Experimental cell research, Vol. 314, Issue 13, pp. 2448-53, (2008) (PubMed).
: "Polycomb complex 2 is required for E-cadherin repression by the Snail1 transcription factor." in: Molecular and cellular biology, Vol. 28, Issue 15, pp. 4772-81, (2008) (PubMed).
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: "Vascular endothelial growth factor-A stimulates Snail expression in breast tumor cells: implications for tumor progression." in: Experimental cell research, Vol. 314, Issue 13, pp. 2448-53, (2008) (PubMed).
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- Target
- SNAIL (SNAI1)
- Andere Bezeichnung
- SNAI1 (SNAI1 Produkte)
- Hintergrund
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Description: Snail is a zinc-finger transcription factor that can repress E-cadherin transcription. Downregulation of E-cadherin is associated with epithelial-mesenchymal transition during embryonic development, a process also exploited by invasive cancer cells . Indeed, loss of E-cadherin expression is correlated with the invasive properties of some tumors and there is a considerable inverse correlation between Snail and E-cadherin mRNA levels in epithelial tumor cell lines . In addition, Snail blocks the cell cycle and confers resistance to cell death . Phosphorylation of Snail by GSK-3 and PAK1 regulates its stability, cellular localization and function .Tissue specificity: Expressed in a variety of tissues with the highest expression in kidney.
Aliases: SNA, SNAH, SLUGH2, dJ710H13.1, SNAI1
- Molekulargewicht
- 29kDa
- Gen-ID
- 6615
- HGNC
- 6615
- UniProt
- O95863
- Pathways
- Negative Regulation of intrinsic apoptotic Signaling
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