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SLUG Antikörper

SNAI2 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 2H5 unconjugated
Produktnummer ABIN969410
  • Target Alle SLUG (SNAI2) Antikörper anzeigen
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    Reaktivität
    • 49
    • 18
    • 13
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 38
    • 11
    Maus
    Klonalität
    • 39
    • 9
    Monoklonal
    Konjugat
    • 31
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Dieser SLUG Antikörper ist unkonjugiert
    Applikation
    • 26
    • 18
    • 12
    • 9
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human SNAI2 expressed in E. coli.
    Klon
    2H5
    Isotyp
    IgG1
    Top Product
    Discover our top product SNAI2 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Saegusa, Hashimura, Kuwata, Okayasu: "Requirement of the Akt/beta-catenin pathway for uterine carcinosarcoma genesis, modulating E-cadherin expression through the transactivation of slug." in: The American journal of pathology, Vol. 174, Issue 6, pp. 2107-15, (2009) (PubMed).

    Medici, Hay, Olsen: "Snail and Slug promote epithelial-mesenchymal transition through beta-catenin-T-cell factor-4-dependent expression of transforming growth factor-beta3." in: Molecular biology of the cell, Vol. 19, Issue 11, pp. 4875-87, (2008) (PubMed).

  • Target
    SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
    Andere Bezeichnung
    SNAI2 (SNAI2 Produkte)
    Synonyme
    Slug antikoerper, Slugh antikoerper, Snail2 antikoerper, snail family transcriptional repressor 2 antikoerper, snail family zinc finger 2 antikoerper, Snai2 antikoerper
    Hintergrund

    Description: This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity.The tumor suppressor protein p53 induces Slug expression in γ-irradiated cells, Slug protects damaged cells from apoptosis by repressing p53-induced transcription of the proapoptotic Bcl-2 family protein Puma. Mutations in this gene may be associated with sporatic cases of neural tube defects.

    Aliases: SLUG, WS2D, SLUGH1, MGC10182, SNAI2

    Molekulargewicht
    30 kDa
    Gen-ID
    6591
    HGNC
    6591
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