TYRO3 Antikörper

Produktnummer ABIN969449

Produktdetails anti-TYRO3 Antikörper

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser TYRO3 Antikörper ist unkonjugiert

Applikation: ELISA

Verwendungszweck: TYRO3 Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant extracellular fragment of human TYRO3 fused with hIgGFc tag expressed in HEK293 cell line.

Klon: 10E11

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-TYRO3 Antikörper (ABIN969449)

Lan, Wu, Li, Wu, Lu, Xu, Dai: "Transforming activity of receptor tyrosine kinase tyro3 is mediated, at least in part, by the PI3 kinase-signaling pathway." in: Blood, Vol. 95, Issue 2, pp. 633-8, (2000) (PubMed).

Details zu TYRO3

Target: TYRO3 (TYRO3 Protein Tyrosine Kinase (TYRO3))

Andere Bezeichnung: TYRO3 (TYRO3 Produkte)

Synonyme: TYRO3 antikoerper, brt antikoerper, byk antikoerper, dtk antikoerper, rse antikoerper, sky antikoerper, tif antikoerper, Xksy antikoerper, MGC145734 antikoerper, DKFZp469I0432 antikoerper, LOC100231598 antikoerper, BYK antikoerper, Dtk antikoerper, RSE antikoerper, Sky antikoerper, Tif antikoerper, Brt antikoerper, REK antikoerper, ksy antikoerper, xksy antikoerper, AI323366 antikoerper, Etk-2 antikoerper, Rse antikoerper, TYRO3 protein tyrosine kinase antikoerper, TYRO3 protein tyrosine kinase L homeolog antikoerper, TYRO3 protein tyrosine kinase 3 antikoerper, TYRO3 antikoerper, tyro3 antikoerper, Tyro3 antikoerper, tyro3.L antikoerper

Hintergrund:

Description: TYRO3: Tyrosine-protein kinase, also known as BYK, Brt, Dtk, Sky. Entrez Protein: NP_006284. It belongs to the Tyr protein kinase family (AXL/UFO subfamily). The UFO family of receptor tyrosine kinases is comprised of subfamily members Rse(also referred to as Tyro3 or Sky) and UFO (also called Tyro7 or Axl). Two distinct isoforms of Rse, designated Brt and Etk-2, have been described. Brt differs from Rse at its C-terminus, but more importantly lacks the N-terminal 31 amino acid signal peptide sequence present in Rse, which is replaced by a 27 amino acid Brt-specific sequence. It has been suggested that as a result of this alternative splicing event, Brt resides in the cytoplasm, unlike Rse which is expressed on the cell surface. Ekt-2 also lacks an N-terminal signal peptide which is substituted with a 45 amino acid Ekt-2-specific sequence. Protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation.

Aliases: BYK, Brt, Dtk, RSE, Sky, Tif

Molekulargewicht: 96.9kDa

Gen-ID: 7301

HGNC: 7301

UniProt: Q06418

Pathways: RTK Signalweg