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Vimentin Antikörper

Name: Vimentin Antikörper
Brand: antibodies-online
SKU: ABIN969453
Price: 587.53 EUR
Availability: InStock

VIM Reaktivität: Human WB, IHC, ELISA Wirt: Maus Monoclonal 9E7E7 unconjugated

Western blot analysis using Vimentin mouse mAb against truncated Vimentin recombinant protein. (Vimentin Antikörper)

Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue, showing cytoplasmic localization using Vimentin mouse mAb with DAB staining. (Vimentin Antikörper)

IHC

2 Abbildungen

(1 reference)

Produktnummer ABIN969453

Datenblatt (PDF)

Target Alle Vimentin (VIM) Antikörper anzeigen

Vimentin (VIM)
Reaktivität
306

121

118

61

60

50

43

38

30

22

20

14

13

8

8

6

6

3

3

2

1

1

1

1

1

1

1

1

1
Human
Wirt
158

131

11

6

6

5

2
Maus
Passende Sekundärantikörper
Klonalität
172

146
Monoklonal
Konjugat
199

15

13

12

9

7

3

3

3

3

3

3

3

3

3

3

3

3

2

2

2

2

2

2

2

2

2

2

2

2

2

1

1
Dieser Vimentin Antikörper ist unkonjugiert
Applikation
264

115

105

98

88

64

48

40

39

33

23

20

8

5

4

4

3

2

2

2

1

1

1

1

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Verwendungszweck

Vimentin Antibody

Aufreinigung

Ascitic fluid

Immunogen

Purified recombinant fragment of Vimentin expressed in E. Coli.

Klon

9E7E7

Isotyp

IgG1

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anti-Vimentin (VIM) antibody
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anti-Vimentin (VIM) antibody
VIM Reaktivität: Säugetier WB, FACS, IHC (p), ICC Wirt: Maus Monoclonal VI-01 unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Human, Maus, Ratte, Schwein, Huhn WB, IHC (p), ICC, IP Wirt: Maus Monoclonal VI-10 unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Human, Maus WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB41034 unconjugated

anti-Vimentin (VIM) (AA 1-200) antibody
VIM Reaktivität: Human WB, IHC, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Vimentin (VIM) antibody
VIM Reaktivität: Human WB, IHC, ICC, IP Wirt: Maus Monoclonal C8 unconjugated

anti-Vimentin (VIM) (AA 430-457), (C-Term) antibody
VIM Reaktivität: Human WB, IF, FACS, IHC (p) Wirt: Kaninchen Polyclonal RB16691 unconjugated

anti-Vimentin (VIM) (AA 41-140) antibody
VIM Reaktivität: Human WB, ELISA, IF, IP Wirt: Maus Monoclonal 3E9 unconjugated

anti-Vimentin (VIM) (AA 2-466) antibody
VIM Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 3A1F2 unconjugated

Applikationshinweise

ELISA: 1/10000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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Target

Vimentin (VIM)

Andere Bezeichnung

Vimentin (VIM Produkte)

Hintergrund

Description: Vimentin is the major subunit protein of the intermediate filaments of mesenchymal cells. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis. Immunohistochemical staining for Vimentin is characteristic of sarcomas (of neural, muscle and fibroblast origin) compared to carcinomas which are generally negative. Melanomas, lymphomas and vascular tumors may all stain for Vimentin. Vimentin antibodies are thus of value in the differential diagnosis of undifferentiated neoplasms and malignant tumors. They are generally used with a panel of other antibodies including those recognising cytokeratins, lymphoid markers, S100, desmin and neurofilaments.
Aliases: FLJ36605, VIM

Gen-ID

7431

HGNC

7431

UniProt

P08670

Pathways

Caspase Kaskade in der Apoptose