WDR5 Antikörper
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- Target Alle WDR5 Antikörper anzeigen
- WDR5 (WD Repeat Domain 5 (WDR5))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser WDR5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA
- Aufreinigung
- purified
- Immunogen
- Purified recombinant fragment of human WDR5 expressed in E. coli.
- Klon
- 7B11
- Isotyp
- IgG2b
- Top Product
- Discover our top product WDR5 Primärantikörper
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- Applikationshinweise
- ELISA: 1:10000, WB: 1:500 - 1:2000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
- 4°C, -20°C for long term storage
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A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex." in: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 32162-75, (2008) (PubMed).
: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).
: "
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A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex." in: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 32162-75, (2008) (PubMed).
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- Target
- WDR5 (WD Repeat Domain 5 (WDR5))
- Andere Bezeichnung
- WDR5 (WDR5 Produkte)
- Synonyme
- BIG-3 antikoerper, SWD3 antikoerper, 2410008O07Rik antikoerper, AA408785 antikoerper, AA960360 antikoerper, Big antikoerper, Big-3 antikoerper, zgc:56591 antikoerper, zgc:76895 antikoerper, wu:fk47f04 antikoerper, wdr5-a antikoerper, MGC80538 antikoerper, wdr5-b antikoerper, MGC81485 antikoerper, big-3 antikoerper, swd3 antikoerper, xwdr5 antikoerper, WDR5B antikoerper, WD repeat domain 5 antikoerper, WD repeat domain 5 L homeolog antikoerper, WD repeat domain 5 S homeolog antikoerper, WDR5 antikoerper, Wdr5 antikoerper, wdr5 antikoerper, wdr5.L antikoerper, wdr5.S antikoerper
- Hintergrund
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Description: WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.
Aliases: SWD3, BIG-3, WDR5
- Molekulargewicht
- 36.6 kDa
- Gen-ID
- 11091
- HGNC
- 11091
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