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WDR5 Antikörper

WDR5 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 7B11 unconjugated
Produktnummer ABIN969456
  • Target Alle WDR5 Antikörper anzeigen
    WDR5 (WD Repeat Domain 5 (WDR5))
    Reaktivität
    • 63
    • 34
    • 26
    • 4
    • 4
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 58
    • 4
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 52
    • 12
    • 1
    Monoklonal
    Konjugat
    • 35
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser WDR5 Antikörper ist unkonjugiert
    Applikation
    • 40
    • 30
    • 11
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human WDR5 expressed in E. coli.
    Klon
    7B11
    Isotyp
    IgG2b
    Top Product
    Discover our top product WDR5 Primärantikörper
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Patel, Vought, Dharmarajan, Cosgrove: "A conserved arginine-containing motif crucial for the assembly and enzymatic activity of the mixed lineage leukemia protein-1 core complex." in: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 32162-75, (2008) (PubMed).

    Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

  • Target
    WDR5 (WD Repeat Domain 5 (WDR5))
    Andere Bezeichnung
    WDR5 (WDR5 Produkte)
    Synonyme
    BIG-3 antikoerper, SWD3 antikoerper, 2410008O07Rik antikoerper, AA408785 antikoerper, AA960360 antikoerper, Big antikoerper, Big-3 antikoerper, zgc:56591 antikoerper, zgc:76895 antikoerper, wu:fk47f04 antikoerper, wdr5-a antikoerper, MGC80538 antikoerper, wdr5-b antikoerper, MGC81485 antikoerper, big-3 antikoerper, swd3 antikoerper, xwdr5 antikoerper, WDR5B antikoerper, WD repeat domain 5 antikoerper, WD repeat domain 5 L homeolog antikoerper, WD repeat domain 5 S homeolog antikoerper, WDR5 antikoerper, Wdr5 antikoerper, wdr5 antikoerper, wdr5.L antikoerper, wdr5.S antikoerper
    Hintergrund

    Description: WD-repeat protein 5 (WDR5, also designated BMP-2-induced gene 3 kb or BIG-3) belongs to the family of WD-40 repeat proteins, and is essential for vertebrate development, Hox gene activation and global H3K4 trimethylation. WDR5 is a conserved subunit of Trithorax (TRX) histone methyltransferase complexes that selectively binds to dimethylated Lys4 (K4me2) in Histone H3 to promote K4 trimethylation by TRX. It is expressed in osteoblasts, chondrocytes, osteocytes and marrow stromal cells. The WDR5 protein contains 7 WD-repeats, which may play a role in its function of accelerating osteoblast differentiation.

    Aliases: SWD3, BIG-3, WDR5

    Molekulargewicht
    36.6 kDa
    Gen-ID
    11091
    HGNC
    11091
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