Desmin Antikörper

Produktnummer ABIN969477

Produktdetails anti-Desmin Antikörper

Target: Desmin (DES)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Desmin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Verwendungszweck: Desmin Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of Desmin expressed in E. Coli.

Klon: 10H7D2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: ELISA: 1/10000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-Desmin Antikörper (ABIN969477)

Shardonofsky, Capetanaki, Boriek: "Desmin modulates lung elastic recoil and airway responsiveness." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 290, Issue 5, pp. L890-6, (2006) (PubMed).

Huang, Li, Foster, Lemanski, Dube, Zhang, Lemanski: "Protein kinase C-mediated desmin phosphorylation is related to myofibril disarray in cardiomyopathic hamster heart." in: Experimental biology and medicine (Maywood, N.J.), Vol. 227, Issue 11, pp. 1039-46, (2002) (PubMed).

Details zu Desmin

Target: Desmin (DES)

Andere Bezeichnung: Desmin (DES Produkte)

Synonyme: DES antikoerper, des-b antikoerper, MGC80853 antikoerper, des antikoerper, csm1 antikoerper, csm2 antikoerper, desm antikoerper, cmd1i antikoerper, MGC75911 antikoerper, LOC100220724 antikoerper, desmin antikoerper, cb290 antikoerper, fb59a12 antikoerper, wu:fb59a12 antikoerper, zgc:109859 antikoerper, CSM1 antikoerper, CSM2 antikoerper, LGMD2R antikoerper, wu:fc11d08 antikoerper, zgc:154009 antikoerper, des-a antikoerper, MGC52614 antikoerper, desmin antikoerper, desmin, gene 1 L homeolog antikoerper, desmin, gene 1 antikoerper, desmin a antikoerper, desmin b antikoerper, desmin, gene 1 S homeolog antikoerper, desmin, gene 2 S homeolog antikoerper, DES antikoerper, des.1.L antikoerper, des.1 antikoerper, des antikoerper, desma antikoerper, Des antikoerper, desmb antikoerper, des.1.S antikoerper, des.2.S antikoerper

Hintergrund:

Description: Desmin (DES), with 470-amino acid protein (about 52 kDa), belongs to the intermediate filament family and Desmin is class III intermediate filaments found in muscle cells. Homopolymers of Desmin form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane.Mutations in Desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.Desmin is also expressed in smooth muscle cells of both airways and alveolar ducts and Desmin is a load-bearing protein that stiffens the airways and consequently the lung and modulates airway contractile response.

Aliases: Desmin

Gen-ID: 1674

HGNC: 1674

UniProt: P17661