EIF4B Antikörper

Produktnummer ABIN969517

Produktdetails anti-EIF4B Antikörper

Target: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser EIF4B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Verwendungszweck: EIF4B Antibody

Aufreinigung: Purified antibody

Immunogen: Purified recombinant fragment of human EIF4B expressed in E. Coli.

Klon: 1F5

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

FCM: 1/200 - 1/400

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-EIF4B Antikörper (ABIN969517)

Mokas, Mills, Garreau, Fournier, Robert, Arya, Kaufman, Pelletier, Mazroui: "Uncoupling stress granule assembly and translation initiation inhibition." in: Molecular biology of the cell, Vol. 20, Issue 11, pp. 2673-83, (2009) (PubMed).

Shahbazian, Roux, Mieulet, Cohen, Raught, Taunton, Hershey, Blenis, Pende, Sonenberg: "The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity." in: The EMBO journal, Vol. 25, Issue 12, pp. 2781-91, (2006) (PubMed).

Details zu EIF4B

Target: EIF4B (Eukaryotic Translation Initiation Factor 4B (EIF4B))

Andere Bezeichnung: EIF4B (EIF4B Produkte)

Synonyme: EIF-4B antikoerper, PRO1843 antikoerper, CG10837 antikoerper, Dm-eIF4B antikoerper, Dmel\\CG10837 antikoerper, Eif4B antikoerper, eIF-4B-L antikoerper, eIF-4B-S antikoerper, eIF-4b antikoerper, eIF4B antikoerper, eIF4B-L antikoerper, eIF4B-S antikoerper, eIf4b antikoerper, 2310046H11Rik antikoerper, AL024095 antikoerper, C85189 antikoerper, Eif4a2 antikoerper, eif4b antikoerper, fb15c09 antikoerper, wu:fb15c09 antikoerper, zgc:101532 antikoerper, MGC89384 antikoerper, eukaryotic translation initiation factor 4B antikoerper, eukaryotic initiation factor 4B antikoerper, Eukaryotic initiation factor 4B antikoerper, eukaryotic translation initiation factor 4Bb antikoerper, eukaryotic translation initiation factor 4Ba antikoerper, eukaryotic translation initiation factor 4B S homeolog antikoerper, EIF4B antikoerper, Eif4B antikoerper, eIF-4B antikoerper, Eif4b antikoerper, eif4bb antikoerper, eif4b antikoerper, eif4ba antikoerper, eif4b.S antikoerper, LOC100284982 antikoerper, LOC100380867 antikoerper

Hintergrund:

Description: The eukaryotic translation initiation factor 4B (eIF4B) plays a critical role in recruiting the 40S ribosomal subunit to the mRNA.It functions in close association with eIF4F and eIF4A. It binds near the 5'-terminal cap of mRNA in the presence of eIF4F and ATP. It promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both eIF4A and eIF4F

Aliases: EIF-4B, PRO1843

Molekulargewicht: 80kDa

Gen-ID: 1975

HGNC: 1975

UniProt: P23588