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Glypican 3 Antikörper

Name: Glypican 3 Antikörper
Brand: antibodies-online
SKU: ABIN969523
Price: 614.71 EUR
Availability: InStock

GPC3 Reaktivität: Human WB, FACS, IHC, ELISA, ICC Wirt: Maus Monoclonal 9C2 unconjugated

Western blot analysis using GPC3 mouse mAb against HepG2 (1), HEK293 (2), Jurkat (3), SK-N-SH (4), PC-12 (5), F9 (6)and Mouse liver (7) cell lysate. (Glypican 3 Antikörper)

Flow cytometric analysis of Jurkat cells using GPC3 mouse mAb (green) and negative control (red). (Glypican 3 Antikörper)

FACS

Immunofluorescence analysis of HeLa cells using GPC3 mouse mAb (green). (Glypican 3 Antikörper)

Immunohistochemical analysis of paraffin-embedded liver cancer tissues using GPC3 mouse mAb with DAB staining. (Glypican 3 Antikörper)

IHC

Immunohistochemical analysis of paraffin-embedded breast cancer tissues using GPC3 mouse mAb with DAB staining. (Glypican 3 Antikörper)

IHC

Western blot analysis using GPC3 mAb against human GPC3 (AA: 55-200) recombinant protein. (Glypican 3 Antikörper)

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (Glypican 3 Antikörper)

ELISA

7 Abbildungen

(2 Referenzen)

Produktnummer ABIN969523

Datenblatt (PDF)

Target Alle Glypican 3 (GPC3) Antikörper anzeigen

Glypican 3 (GPC3)
Reaktivität
143

48

46

4

2

2

2

2

1

1

1
Human
Wirt
89

54

1
Maus
Passende Sekundärantikörper
Klonalität
75

68

1
Monoklonal
Konjugat
58

12

7

6

6

6

5

5

5

5

5

5

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser Glypican 3 Antikörper ist unkonjugiert
Applikation
81

78

63

44

35

26

16

16

6

2

2

1

1
Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunocytochemistry (ICC)

Verwendungszweck

GPC3 Antibody

Aufreinigung

Purified antibody

Immunogen

Purified recombinant fragment of human GPC3 expressed in E. Coli.

Klon

9C2

Isotyp

IgG1
anti-Glypican 3 (GPC3) (AA 344-559) antibody
GPC3 Reaktivität: Maus WB, IHC, ICC, IP Wirt: Kaninchen Polyclonal unconjugated

anti-Glypican 3 (GPC3) (AA 55-200) antibody
GPC3 Reaktivität: Human WB, FACS, IHC, ELISA Wirt: Maus Monoclonal 2A2C3 unconjugated

anti-Glypican 3 (GPC3) (AA 359-554) antibody
GPC3 Reaktivität: Human WB, FACS, IHC, ELISA Wirt: Maus Monoclonal 2C7E9 unconjugated

anti-Glypican 3 (GPC3) antibody
GPC3 Reaktivität: Human, Ratte IF, FACS, IHC, StM Wirt: Maus Monoclonal GPC3-863 unconjugated

anti-Glypican 3 (GPC3) (AA 55-200) antibody
GPC3 Reaktivität: Human IF, WB, FACS, IHC, ELISA, IHC (p) Wirt: Maus Monoclonal 9C2 unconjugated

anti-Glypican 3 (GPC3) (AA 21-50), (N-Term) antibody
GPC3 Reaktivität: Human, Maus WB, IHC (p) Wirt: Kaninchen Polyclonal RB05031 unconjugated

anti-Glypican 3 (GPC3) (AA 359-554) antibody
GPC3 Reaktivität: Human WB, FACS, ELISA Wirt: Maus Monoclonal 4D5B1 unconjugated

anti-Glypican 3 (GPC3) antibody
GPC3 Reaktivität: Human, Ratte IF, FACS, IHC, StM Wirt: Maus Monoclonal rGPC3-863 unconjugated Recombinant Antibody

anti-Glypican 3 (GPC3) (AA 511-580) antibody
GPC3 Reaktivität: Human IF, WB, FACS, IHC, StM Wirt: Maus Monoclonal 1G12 unconjugated

anti-Glypican 3 (GPC3) antibody
GPC3 Reaktivität: Human, Maus IF, WB, IHC (p), EIA Wirt: Maus Monoclonal 9C2 unconjugated

Applikationshinweise

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Zittermann, Capurro, Shi, Filmus: "Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo." in: International journal of cancer. Journal international du cancer, Vol. 126, Issue 6, pp. 1291-301, (2010) (PubMed).

Takai, Ashihara, Ishiguro, Terashima, Watanabe, Kato, Suzuki: "Involvement of glypican-3 in the recruitment of M2-polarized tumor-associated macrophages in hepatocellular carcinoma." in: Cancer biology & therapy, Vol. 8, Issue 24, pp. 2329-38, (2010) (PubMed).
Target

Glypican 3 (GPC3)

Andere Bezeichnung

GPC3 (GPC3 Produkte)

Synonyme

GPC3 antikoerper, sgb antikoerper, dgsx antikoerper, sdys antikoerper, sgbs antikoerper, oci-5 antikoerper, sgbs1 antikoerper, DGSX antikoerper, GTR2-2 antikoerper, MXR7 antikoerper, OCI-5 antikoerper, SDYS antikoerper, SGB antikoerper, SGBS antikoerper, SGBS1 antikoerper, Glypican-3 antikoerper, glypican 3 antikoerper, gpc3 antikoerper, GPC3 antikoerper, Gpc3 antikoerper

Hintergrund

Description: Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.
Aliases: SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2

Molekulargewicht

65.5kDa

Gen-ID

2719

HGNC

2719

UniProt

P51654

Pathways

Glycosaminoglycan Metabolic Process