Hexosaminidase A Antikörper
-
- Target Alle Hexosaminidase A (HEXA) Antikörper anzeigen
- Hexosaminidase A (HEXA)
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser Hexosaminidase A Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- HEXA Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human HEXA expressed in E. Coli.
- Klon
- 3F10
- Isotyp
- IgG2b
- Top Product
- Discover our top product HEXA Primärantikörper
-
-
- Applikationshinweise
-
ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
Improving accuracy of Tay Sachs carrier screening of the non-Jewish population: analysis of 34 carriers and six late-onset patients with HEXA enzyme and DNA sequence analysis." in: Pediatric research, Vol. 67, Issue 2, pp. 217-20, (2010) (PubMed).
: "Hexosaminidase as a new potential marker for larynx cancer." in: Clinical biochemistry, Vol. 42, Issue 10-11, pp. 1187-9, (2009) (PubMed).
: "
-
Improving accuracy of Tay Sachs carrier screening of the non-Jewish population: analysis of 34 carriers and six late-onset patients with HEXA enzyme and DNA sequence analysis." in: Pediatric research, Vol. 67, Issue 2, pp. 217-20, (2010) (PubMed).
-
- Target
- Hexosaminidase A (HEXA)
- Andere Bezeichnung
- HEXA (HEXA Produkte)
- Synonyme
- TSD antikoerper, fc04h11 antikoerper, wu:fc04h11 antikoerper, wu:fv09f06 antikoerper, si:dkey-35i22.2 antikoerper, HEXA antikoerper, Hex-1 antikoerper, zgc:112084 antikoerper, hexosaminidase subunit alpha antikoerper, hexosaminidase B (beta polypeptide) antikoerper, CUGBP Elav-like family member 6 antikoerper, hexosaminidase A antikoerper, hexosaminidase A (alpha polypeptide) antikoerper, beta-hexosaminidase subunit alpha-like antikoerper, HEXA antikoerper, hexb antikoerper, CELF6 antikoerper, Hexa antikoerper, hexa antikoerper, LOC100228061 antikoerper
- Hintergrund
-
Description: This gene encodes the alpha subunit of the lysosomal enzyme beta-hexosaminidase that, together with the cofactor GM2 activator protein, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Beta-hexosaminidase is composed of two subunits, alpha and beta, which are encoded by separate genes. Both beta-hexosaminidase alpha and beta subunits are members of family 20 of glycosyl hydrolases. Mutations in the alpha or beta subunit genes lead to an accumulation of GM2 ganglioside in neurons and neurodegenerative disorders termed the GM2 gangliosidoses. Alpha subunit gene mutations lead to Tay-Sachs disease (GM2-gangliosidosis type I).
Aliases: TSD
- Molekulargewicht
- 60.7kDa
- Gen-ID
- 3073
- HGNC
- 3073
- UniProt
- P06865
- Pathways
- Sensory Perception of Sound, Glycosaminoglycan Metabolic Process
-