JNK Antikörper
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- Target Alle JNK (MAPK8) Antikörper anzeigen
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser JNK Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), ELISA, Flow Cytometry (FACS)
- Verwendungszweck
- MAPK8 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human MAPK8 expressed in E. Coli.
- Klon
- 1E5
- Isotyp
- IgG1
- Top Product
- Discover our top product MAPK8 Primärantikörper
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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- Target
- JNK (MAPK8) (Mitogen-Activated Protein Kinase 8 (MAPK8))
- Andere Bezeichnung
- MAPK8 (MAPK8 Produkte)
- Synonyme
- JNK antikoerper, JNK-46 antikoerper, JNK1 antikoerper, JNK1A2 antikoerper, JNK21B1/2 antikoerper, PRKM8 antikoerper, SAPK1 antikoerper, SAPK1c antikoerper, AI849689 antikoerper, Prkm8 antikoerper, BSK antikoerper, BSK/DJNK antikoerper, Bsk antikoerper, CG5680 antikoerper, D-JNK antikoerper, D-junk antikoerper, DBSK/JNK antikoerper, DJNK antikoerper, DJNK/bsk antikoerper, Dmel\\CG5680 antikoerper, JNK/SAPK antikoerper, Jnk antikoerper, Junk antikoerper, SAPKa antikoerper, c-Jun antikoerper, dJNK antikoerper, jnk antikoerper, T10F20.15 antikoerper, jnk1 antikoerper, sapk1 antikoerper, mapk8 antikoerper, zgc:112379 antikoerper, JNKb antikoerper, mapk8b antikoerper, mitogen-activated protein kinase 8 antikoerper, Stress-activated protein kinase jnk-1 antikoerper, basket antikoerper, Protein kinase superfamily protein antikoerper, mitogen-activated protein kinase 8 L homeolog antikoerper, mitogen-activated protein kinase 8b antikoerper, mitogen-activated protein kinase 8B-like antikoerper, MAPK8 antikoerper, jnk-1 antikoerper, Mapk8 antikoerper, bsk antikoerper, ATMPK8 antikoerper, mapk8.L antikoerper, mapk8b antikoerper, LOC109094263 antikoerper
- Hintergrund
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Description: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Aliases: JNK, JNK1, PRKM8, SAPK1, JNK-46, JNK1A2, SAPK1c, JNK21B1/2
- Molekulargewicht
- 48.3kDa
- Gen-ID
- 5599
- HGNC
- 5599
- UniProt
- P45983
- Pathways
- MAPK Signalweg, WNT Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Neurotrophin Signalübertragung, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades, Signaling of Hepatocyte Growth Factor Receptor, S100 Proteine
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