Aktivieren Sie Javascript in Ihrem Browser, um unsere Webseite optimal zu nutzen.

MELK Antikörper (AA 637-651)

Name: MELK Antikörper (AA 637-651)
Brand: antibodies-online
SKU: ABIN969538
Price: 614.71 EUR
Availability: InStock

MELK Reaktivität: Human ELISA, IHC, ICC, FACS Wirt: Maus Monoclonal 2G2 unconjugated

Immunohistochemical analysis of paraffin-embedded liver cancer tissues using MELK mouse mAb with DAB staining. (MELK Antikörper (AA 637-651))

IHC

Black line: Control Antigen (100 ng), Purple line: Antigen(10 ng), Blue line: Antigen (50 ng), Red line: Antigen (100 ng), (MELK Antikörper (AA 637-651))

ELISA

Flow cytometric analysis of MCF-7 cells using MELK mouse mAb (green) and negative control (red). (MELK Antikörper (AA 637-651))

FACS

Immunofluorescence analysis of HepG2 cells using MELK mouse mAb (green). (MELK Antikörper (AA 637-651))

Immunohistochemical analysis of paraffin-embedded rectum cancer tissues using MELK mouse mAb with DAB staining. (MELK Antikörper (AA 637-651))

IHC

5 Abbildungen

(2 Referenzen)

Produktnummer ABIN969538

Datenblatt (PDF)

Target Alle MELK Antikörper anzeigen

MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))
Bindungsspezifität
15

8

8

5

3

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 637-651
Reaktivität
61

18

14

4

4

4

3

3

2

2
Human
Wirt
61

4

1
Maus
Passende Sekundärantikörper
Klonalität
61

5
Monoklonal
Konjugat
35

4

3

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
Dieser MELK Antikörper ist unkonjugiert
Applikation
39

28

13

13

7

6

6

3

3

3

2

1

1

1
ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC), Flow Cytometry (FACS)

Verwendungszweck

MELK Antibody

Sequenz

VYKRLVEDIL SSCKV

Aufreinigung

Purified antibody

Immunogen

Synthesized peptide of human MELK(AA: 637-651:C-VYKRLVEDILSSCKV).

Klon

2G2

Isotyp

IgG2a
anti-Maternal Embryonic Leucine Zipper Kinase (MELK) antibody
MELK Reaktivität: Human ELISA, IHC, IF, FACS Wirt: Maus Monoclonal 2G2 unconjugated

anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 637-651) antibody
MELK Reaktivität: Human ELISA, IHC, FACS, IF/ICC Wirt: Maus Monoclonal unconjugated

anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 434-468), (C-Term) antibody
MELK Reaktivität: Maus WB, FACS Wirt: Kaninchen Polyclonal RB51204 unconjugated

anti-Maternal Embryonic Leucine Zipper Kinase (MELK) antibody
MELK Reaktivität: Human IF, IHC (p), EIA Wirt: Maus Monoclonal 2G2 unconjugated

anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 525-554), (C-Term) antibody
MELK Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB8557 unconjugated

anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (Center) antibody
MELK Reaktivität: Human, Maus, Ratte, Affe WB, IHC, IF, IC Wirt: Kaninchen Polyclonal unconjugated

anti-Maternal Embryonic Leucine Zipper Kinase (MELK) antibody
MELK Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated

anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 101-250) antibody
MELK Reaktivität: Human ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) Wirt: Kaninchen Polyclonal unconjugated

anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 381-415) antibody
MELK Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB51207 unconjugated

anti-Maternal Embryonic Leucine Zipper Kinase (MELK) (AA 201-230) antibody
MELK Reaktivität: Human WB Wirt: Kaninchen Polyclonal RB8556 unconjugated

Applikationshinweise

ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Purified antibody in PBS with 0.05 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C,-20 °C

Informationen zur Lagerung

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Nakano, Joshi, Visnyei, Hu, Watanabe, Lam, Wexler, Saigusa, Nakamura, Laks, Mischel, Viapiano, Kornblum: "Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway." in: Neuro-oncology, Vol. 13, Issue 6, pp. 622-34, (2011) (PubMed).

Pickard, Green, Ellis, Caldas, Hedge, Mourtada-Maarabouni, Williams: "Dysregulated expression of Fau and MELK is associated with poor prognosis in breast cancer." in: Breast cancer research : BCR, Vol. 11, Issue 4, pp. R60, (2009) (PubMed).
Target

MELK (Maternal Embryonic Leucine Zipper Kinase (MELK))

Andere Bezeichnung

MELK (MELK Produkte)

Synonyme

MELK antikoerper, xmelk antikoerper, Melk antikoerper, HPK38 antikoerper, AI327312 antikoerper, MPK38 antikoerper, mKIAA0175 antikoerper, fb71b01 antikoerper, fe01f04 antikoerper, wu:fb71b01 antikoerper, wu:fe01f04 antikoerper, maternal embryonic leucine zipper kinase antikoerper, maternal embryonic leucine zipper kinase L homeolog antikoerper, MELK antikoerper, melk antikoerper, cgd5_2270 antikoerper, Melk antikoerper, melk.L antikoerper

Hintergrund

Description: Maternal embryonic leucine-zipper kinase (MELK) is a key regulator of survival of stemlike GBM cells in vitro. MELK expression is increased in breast cancer tissue and this increase is also associated with poor patient survival, as predicted for a candidate oncogene.
Aliases: HPK38

Molekulargewicht

74.6kDa

Gen-ID

9833

HGNC

9833

UniProt

Q14680