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NEFL Antikörper

NEFL Reaktivität: Human WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 1H3 unconjugated
Produktnummer ABIN969548
  • Target Alle NEFL Antikörper anzeigen
    NEFL (Neurofilament, Light Polypeptide (NEFL))
    Reaktivität
    • 73
    • 51
    • 39
    • 26
    • 24
    • 18
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 58
    • 34
    • 8
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 62
    • 41
    Monoklonal
    Konjugat
    • 64
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NEFL Antikörper ist unkonjugiert
    Applikation
    • 57
    • 39
    • 32
    • 22
    • 16
    • 16
    • 14
    • 13
    • 13
    • 11
    • 11
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Aufreinigung
    purified
    Immunogen
    Purified recombinant fragment of human NEFL expressed in E. coli.
    Klon
    1H3
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, ICC: 1:200 - 1:1000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Lee, Kim, Chung, Kim, Kwon, Min, Chang: "The effect of rod domain A148V mutation of neurofilament light chain on filament formation." in: BMB reports, Vol. 41, Issue 12, pp. 868-74, (2009) (PubMed).

    Abe, Numakura, Saito, Koide, Oka, Honma, Kishikawa, Hayasaka: "Neurofilament light chain polypeptide gene mutations in Charcot-Marie-Tooth disease: nonsense mutation probably causes a recessive phenotype." in: Journal of human genetics, Vol. 54, Issue 2, pp. 94-7, (2009) (PubMed).

  • Target
    NEFL (Neurofilament, Light Polypeptide (NEFL))
    Andere Bezeichnung
    NEFL (NEFL Produkte)
    Synonyme
    NEFL antikoerper, nefl antikoerper, zgc:136626 antikoerper, AI847934 antikoerper, CMT2E antikoerper, NF-L antikoerper, NF68 antikoerper, Nfl antikoerper, CMT1F antikoerper, NFL antikoerper, XNF-L antikoerper, neurofilament light antikoerper, neurofilament, light polypeptide antikoerper, neurofilament, light polypeptide b antikoerper, neurofilament, light L homeolog antikoerper, NEFL antikoerper, neflb antikoerper, Nefl antikoerper, nefl.L antikoerper
    Hintergrund

    Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

    Aliases: NFL, NF-L, NF68, CMT1F, CMT2E

    Molekulargewicht
    62 kDa
    Gen-ID
    4747
    HGNC
    4747
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