NEFL Antikörper
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- Target Alle NEFL Antikörper anzeigen
- NEFL (Neurofilament, Light Polypeptide (NEFL))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser NEFL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
- Verwendungszweck
- NEFL Antibody
- Aufreinigung
- Ascitic fluid
- Immunogen
- Purified recombinant fragment of human NEFL expressed in E. Coli.
- Klon
- 1H3
- Isotyp
- IgG1
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- Applikationshinweise
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ELISA: 1/10000
FCM: 1/200 - 1/400
ICC: 1/200 - 1/1000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Ascitic fluid containing 0.03 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
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The effect of rod domain A148V mutation of neurofilament light chain on filament formation." in: BMB reports, Vol. 41, Issue 12, pp. 868-74, (2009) (PubMed).
: "Neurofilament light chain polypeptide gene mutations in Charcot-Marie-Tooth disease: nonsense mutation probably causes a recessive phenotype." in: Journal of human genetics, Vol. 54, Issue 2, pp. 94-7, (2009) (PubMed).
: "
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The effect of rod domain A148V mutation of neurofilament light chain on filament formation." in: BMB reports, Vol. 41, Issue 12, pp. 868-74, (2009) (PubMed).
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- Target
- NEFL (Neurofilament, Light Polypeptide (NEFL))
- Andere Bezeichnung
- NEFL (NEFL Produkte)
- Synonyme
- NEFL antikoerper, nefl antikoerper, zgc:136626 antikoerper, AI847934 antikoerper, CMT2E antikoerper, NF-L antikoerper, NF68 antikoerper, Nfl antikoerper, CMT1F antikoerper, NFL antikoerper, XNF-L antikoerper, neurofilament light antikoerper, neurofilament, light polypeptide antikoerper, neurofilament, light polypeptide b antikoerper, neurofilament, light L homeolog antikoerper, NEFL antikoerper, neflb antikoerper, Nefl antikoerper, nefl.L antikoerper
- Hintergrund
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Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.
Aliases: NFL, NF-L, NF68, CMT1F, CMT2E
- Molekulargewicht
- 62kDa
- Gen-ID
- 4747
- HGNC
- 4747
- UniProt
- P07196
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