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NEFL Antikörper

NEFL Reaktivität: Human WB, IHC, ELISA, FACS, ICC Wirt: Maus Monoclonal 1H3 unconjugated
Produktnummer ABIN969548
  • Target Alle NEFL Antikörper anzeigen
    NEFL (Neurofilament, Light Polypeptide (NEFL))
    Reaktivität
    • 72
    • 50
    • 38
    • 26
    • 24
    • 18
    • 4
    • 2
    • 2
    • 1
    • 1
    Human
    Wirt
    • 57
    • 34
    • 8
    • 1
    • 1
    • 1
    Maus
    Klonalität
    • 61
    • 41
    Monoklonal
    Konjugat
    • 63
    • 9
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NEFL Antikörper ist unkonjugiert
    Applikation
    • 56
    • 39
    • 31
    • 21
    • 16
    • 15
    • 14
    • 13
    • 13
    • 11
    • 11
    • 10
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Flow Cytometry (FACS), Immunocytochemistry (ICC)
    Verwendungszweck
    NEFL Antibody
    Aufreinigung
    Ascitic fluid
    Immunogen
    Purified recombinant fragment of human NEFL expressed in E. Coli.
    Klon
    1H3
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    ICC: 1/200 - 1/1000

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Ascitic fluid containing 0.03 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Lee, Kim, Chung, Kim, Kwon, Min, Chang: "The effect of rod domain A148V mutation of neurofilament light chain on filament formation." in: BMB reports, Vol. 41, Issue 12, pp. 868-74, (2009) (PubMed).

    Abe, Numakura, Saito, Koide, Oka, Honma, Kishikawa, Hayasaka: "Neurofilament light chain polypeptide gene mutations in Charcot-Marie-Tooth disease: nonsense mutation probably causes a recessive phenotype." in: Journal of human genetics, Vol. 54, Issue 2, pp. 94-7, (2009) (PubMed).

  • Target
    NEFL (Neurofilament, Light Polypeptide (NEFL))
    Andere Bezeichnung
    NEFL (NEFL Produkte)
    Synonyme
    NEFL antikoerper, nefl antikoerper, zgc:136626 antikoerper, AI847934 antikoerper, CMT2E antikoerper, NF-L antikoerper, NF68 antikoerper, Nfl antikoerper, CMT1F antikoerper, NFL antikoerper, XNF-L antikoerper, neurofilament light antikoerper, neurofilament, light polypeptide antikoerper, neurofilament, light polypeptide b antikoerper, neurofilament, light L homeolog antikoerper, NEFL antikoerper, neflb antikoerper, Nefl antikoerper, nefl.L antikoerper
    Hintergrund

    Description: Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and they functionally maintain the neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the light chain neurofilament protein. Mutations in this gene cause Charcot-Marie-Tooth disease types 1F (CMT1F) and 2E (CMT2E), disorders of the peripheral nervous system that are characterized by distinct neuropathies. A pseudogene has been identified on chromosome Y.

    Aliases: NFL, NF-L, NF68, CMT1F, CMT2E

    Molekulargewicht
    62kDa
    Gen-ID
    4747
    HGNC
    4747
    UniProt
    P07196
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