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RAP1A Antikörper

RAP1A Reaktivität: Human ELISA, FACS Wirt: Maus Monoclonal 5F8 unconjugated
Produktnummer ABIN969561
  • Target Alle RAP1A Antikörper anzeigen
    RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
    Reaktivität
    • 47
    • 47
    • 17
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 57
    • 4
    Maus
    Klonalität
    • 58
    • 3
    Monoklonal
    Konjugat
    • 25
    • 5
    • 5
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RAP1A Antikörper ist unkonjugiert
    Applikation
    • 48
    • 23
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Flow Cytometry (FACS)
    Verwendungszweck
    RAP1A Antibody
    Aufreinigung
    Purified antibody
    Immunogen
    Purified recombinant fragment of human RAP1A expressed in E. Coli.
    Klon
    5F8
    Isotyp
    IgG1
  • Applikationshinweise

    ELISA: 1/10000

    FCM: 1/200 - 1/400

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified antibody in PBS with 0.05 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
  • Severson, Lee, Capaldo, Nusrat, Parkos: "Junctional adhesion molecule A interacts with Afadin and PDZ-GEF2 to activate Rap1A, regulate beta1 integrin levels, and enhance cell migration." in: Molecular biology of the cell, Vol. 20, Issue 7, pp. 1916-25, (2009) (PubMed).

    Dao, Dupuy, Gavet, Caron, de Gunzburg: "Dynamic changes in Rap1 activity are required for cell retraction and spreading during mitosis." in: Journal of cell science, Vol. 122, Issue Pt 16, pp. 2996-3004, (2009) (PubMed).

  • Target
    RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))
    Andere Bezeichnung
    RAP1A (RAP1A Produkte)
    Synonyme
    KREV-1 antikoerper, KREV1 antikoerper, RAP1 antikoerper, SMGP21 antikoerper, AI848598 antikoerper, G-22K antikoerper, Krev-1 antikoerper, Rap1 antikoerper, RAP-1A antikoerper, rap 1A antikoerper, wu:fc66g06 antikoerper, zgc:86676 antikoerper, krev-1 antikoerper, krev1 antikoerper, rap1 antikoerper, RAP1A, member of RAS oncogene family antikoerper, RAS-related protein 1a antikoerper, RAP1A, member of RAS oncogene family a antikoerper, RAP1A, member of RAS oncogene family L homeolog antikoerper, RAP1A antikoerper, Rap1a antikoerper, rap1aa antikoerper, rap1a.L antikoerper
    Hintergrund

    Description: The product of this gene belongs to the family of RAS-related proteins. These proteins share approximately 50 % amino acid identity with the classical RAS proteins and have numerous structural features in common. The most striking difference between RAP proteins and RAS proteins resides in their 61st amino acid: glutamine in RAS is replaced by threonine in RAP proteins. The product of this gene counteracts the mitogenic function of RAS because it can interact with RAS GAPs and RAF in a competitive manner. Two transcript variants encoding the same protein have been identified for this gene.

    Aliases: RAP1, KREV1, KREV-1, SMGP21

    Molekulargewicht
    21kDa
    Gen-ID
    5906
    HGNC
    5906
    UniProt
    P62834
    Pathways
    T-Zell Rezeptor Signalweg, Neurotrophin Signalübertragung, Signaling of Hepatocyte Growth Factor Receptor
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