ROCK1 Antikörper
(2 Referenzen)-
- Target Alle ROCK1 Antikörper anzeigen
- ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
-
Reaktivität
- Human
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser ROCK1 Antikörper ist unkonjugiert
-
Applikation
- ELISA
- Verwendungszweck
- ROCK1 Antibody
- Aufreinigung
- Purified antibody
- Immunogen
- Purified recombinant fragment of human ROCK1 expressed in E. Coli.
- Klon
- 1H4
- Isotyp
- IgG1
- Top Product
- Discover our top product ROCK1 Primärantikörper
-
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (N-Term) antibody
KO Validated ROCK1 Reaktivität: Human WB, IP, IF, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 1001-1200) antibodyROCK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 401-510) antibodyROCK1 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2E2 unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (pSer456), (pThr455) antibodyROCK1 Reaktivität: Human, Maus, Ratte WB, ELISA, IF (cc), IF (p), FACS, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 400-660) antibodyROCK1 Reaktivität: Human WB, IHC, IP Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 405-668) antibodyROCK1 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 1094-1323) antibodyROCK1 Reaktivität: Maus WB, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) antibodyROCK1 Reaktivität: Human, Maus, Ratte WB, IHC, IP, IF, FACS, ICC Wirt: Kaninchen Monoclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (Internal Region) antibodyROCK1 Reaktivität: Human, Maus, Ratte, Affe WB, ELISA, IHC, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1) (AA 1114-1126) antibodyROCK1 Reaktivität: Human, Maus, Ratte, Affe, Rind (Kuh), Fledermaus, Hund, Pferd WB Wirt: Maus Monoclonal 154C1465 unconjugated
-
- Applikationshinweise
- ELISA: 1/10000
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Buffer
- Purified antibody in PBS with 0.05 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
-
-
: "Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis." in: American journal of physiology. Heart and circulatory physiology, Vol. 296, Issue 3, pp. H893-9, (2009) (PubMed).
: "Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion." in: Cancer metastasis reviews, Vol. 28, Issue 1-2, pp. 65-76, (2009) (PubMed).
-
: "Inhibition of Rho-dependent kinases ROCK I/II activates VEGF-driven retinal neovascularization and sprouting angiogenesis." in: American journal of physiology. Heart and circulatory physiology, Vol. 296, Issue 3, pp. H893-9, (2009) (PubMed).
-
- Target
- ROCK1 (rho-Associated, Coiled-Coil Containing Protein Kinase 1 (ROCK1))
- Andere Bezeichnung
- ROCK1 (ROCK1 Produkte)
- Hintergrund
-
Description: This gene encodes a protein serine/threonine kinase that is activated when bound to the GTP-bound form of Rho. The small GTPase Rho regulates formation of focal adhesions and stress fibers of fibroblasts, as well as adhesion and aggregation of platelets and lymphocytes by shuttling between the inactive GDP-bound form and the active GTP-bound form. Rho is also essential in cytokinesis and plays a role in transcriptional activation by serum response factor. This protein, a downstream effector of Rho, phosphorylates and activates LIM kinase, which in turn, phosphorylates cofilin, inhibiting its actin-depolymerizing activity. ,
Aliases: ROCK-I, PRO0435, MGC43611, P160ROCK, MGC131603
- Molekulargewicht
- 158kDa
- Gen-ID
- 6093
- HGNC
- 6093
- UniProt
- Q13464
- Pathways
- Microtubule Dynamics, WNT Signalweg, M Phase, Maintenance of Protein Location, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling
-
