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T Antigen (AA 218-352) Antikörper

Reaktivität: Human WB, ELISA, FACS Wirt: Maus Monoclonal 6C12 unconjugated
Produktnummer ABIN969569
  • Target
    T Antigen
    Bindungsspezifität
    • 8
    • 7
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 218-352
    Reaktivität
    • 17
    • 2
    Human
    Wirt
    • 11
    • 7
    Maus
    Klonalität
    • 12
    • 6
    Monoklonal
    Konjugat
    • 13
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 17
    • 9
    • 7
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Flow Cytometry (FACS)
    Aufreinigung
    Purified
    Immunogen
    Purified recombinant fragment of human T (AA 218-352) expressed in E. Coli.
    Klon
    6C12
    Isotyp
    IgG1
  • Applikationshinweise
    ELISA: 1:10000, WB: 1:500 - 1:2000, FCM: 1:200 - 1:400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    PBS with 0.05 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    4°C, -20°C for long term storage
  • Shen, Li, Yang, Lu, Zou, Wang, Deng: "Classic chordoma coexisting with benign notochordal cell rest demonstrating different immunohistological expression patterns of brachyury and galectin-3." in: Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia, Vol. 18, Issue 1, pp. 96-9, (2010) (PubMed).

    Tirabosco, Mangham, Rosenberg, Vujovic, Bousdras, Pizzolitto, De Maglio, den Bakker, Di Francesco, Kalil, Athanasou, ODonnell, McCarthy, Flanagan: "Brachyury expression in extra-axial skeletal and soft tissue chordomas: a marker that distinguishes chordoma from mixed tumor/myoepithelioma/parachordoma in soft tissue." in: The American journal of surgical pathology, Vol. 32, Issue 4, pp. 572-80, (2008) (PubMed).

  • Target
    T Antigen
    Hintergrund
    The protein encoded by this gene is an embryonic nuclear transcription factor that binds to a specific DNA element, the palindromic T-site. It binds through a region in its N-terminus, called the T-box, and effects transcription of genes required for mesoderm formation and differentiation. The protein is localized to notochord-derived cells.
    Molekulargewicht
    47.4 kDa
    Gen-ID
    6862
    HGNC
    6862
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