APAF1 Produkte
(Apoptotic Peptidase Activating Factor 1 (APAF1))
Kategorien
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain (NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].
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Ausgewählte APAF1 Kategorien
APAF1 Antikörper
High quality antibodies with extensive validation data.
APAF1 ELISA Kits
Reliable ELISA kits for a wide range of species.
APAF1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene APAF1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (7)
Kat. Nr.
ABIN1678685
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IHC (p), ICC, IHC (fro)
Validierungen
- (5)
Kat. Nr.
ABIN7433081
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, ICC, FACS
Validierungen
- (5)
Kat. Nr.
ABIN5611196
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene APAF1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964972
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964971
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953881
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene APAF1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345275
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Rat
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7411675
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7393076
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren APAF1 Produkten
: "Optimization of Experimental Variables Influencing Apoptosome Biosensor in HEK293T Cells." in: Sensors (Basel, Switzerland), Vol. 20, Issue 6, (2020) (PubMed).: "A new split-luciferase complementation assay identifies pentachlorophenol as an inhibitor of apoptosome formation." in: FEBS open bio, Vol. 9, Issue 7, pp. 1194-1203, (2020) (PubMed).
: "Apoptosome formation upon overexpression of native and truncated Apaf-1 in cell-free and cell-based systems." in: Archives of biochemistry and biophysics, Vol. 642, pp. 46-51, (2019) (PubMed).
: "LY333531, a PKCβ inhibitor, attenuates glomerular endothelial cell apoptosis in the early stage of mouse diabetic nephropathy via down-regulating swiprosin-1." in: Acta pharmacologica Sinica, Vol. 38, Issue 7, pp. 1009-1023, (2018) (PubMed).
: "Retrotransposon insertions in the clonal evolution of pancreatic ductal adenocarcinoma." in: Nature medicine, Vol. 21, Issue 9, pp. 1060-4, (2015) (PubMed).
: "Expression of SIRT1 and apoptosis-related proteins is predictive for lymph node metastasis and disease-free survival in luminal A breast cancer." in: Virchows Archiv : an international journal of pathology, Vol. 467, Issue 5, pp. 563-70, (2015) (PubMed).
: "Human interleukin 23 receptor induces cell apoptosis in mammalian cells by intrinsic mitochondrial pathway associated with the down-regulation of RAS/mitogen-activated protein kinase and signal ..." in: International journal of molecular sciences, Vol. 14, Issue 12, pp. 24656-69, (2014) (PubMed).
: "[Intralobar sequestration in elderly patient, report of a case]" in: Kyobu geka. The Japanese journal of thoracic surgery, Vol. 61, Issue 9, pp. 812-5, (2008) (PubMed).
: "Calcium blocks formation of apoptosome by preventing nucleotide exchange in Apaf-1." in: Molecular cell, Vol. 25, Issue 2, pp. 181-92, (2007) (PubMed).
: "Mechanical aspects of apoptosome assembly." in: Current opinion in cell biology, Vol. 18, Issue 6, pp. 677-84, (2006) (PubMed).
Synonyme und alternative Namen zu APAF1
Death-associated APAF1-related killer (Dark), apoptotic peptidase activating factor 1 L homeolog (apaf1.L), apoptotic peptidase activating factor 1 (apaf1), apoptotic peptidase activating factor 1 (APAF1), apoptotic peptidase activating factor 1 (Apaf1), 6230400I06Rik, anon-53Fa, Apaf-1, apaf-1, APAF-1, APAF1, Apaf1, apaf1, Apaf1l, arc, ARK, ark, CED4, CG6829, D-Apaf-1, dapaf, Dapaf-1, dAPAF-1, dApaf-1, dapaf-1, dApaf-1/DARK/HAC-1, Dapaf-1/HAC-1, dapaf-1L, dapaf-1S, dApaf1, DARK, Dark, dArk, dark, Dark/Apaf-I, dark/dapaf-1/hac-1, Dark/Dapaf-1/HAC1, Dark/Hac-1/dApaf-1, dark/hac-1/dapaf-1, Dark/Hac-1/dApaf1, Dmel\\CG6829, fog, Hac-1, hac-1, Hac-1/Dark, Hac1, hac1, l(2)SH0173, mKIAA0413, T1, zgc:136543Bezeichner auf Proteinebene für APAF1
- Apaf-1 related
- Apaf-1 related killer
- Apaf-1-related killer
- Ark-PA
- Ark-PB
- CG6829-PA
- CG6829-PB
- apaf1-related killer
- dark
- drosophila Apaf-1-related killer
- lethal (2) SH0173
- transcription unit 1
- apoptotic peptidase activating factor 1
- apoptotic protease-activating factor 1-like
- apoptotic protease-activating factor 1
- apoptotic protease activating factor 1
- forebrain overgrowth
- apaf-1
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