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APBA1 Produkte

(Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 1 (APBA1))

Kategorien

The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. [provided by RefSeq, Jul 2008].

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Ausgewählte APBA1 Kategorien

APBA1 Antikörper

High quality antibodies with extensive validation data.

Empfohlene APBA1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse, Rat
Applikation WB, IHC, ICC
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN1742315
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IHC (p)
Validierungen
  • (2)
Kat. Nr. ABIN6736687
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (3)
Kat. Nr. ABIN2792284
Menge 100 μL
Datenblatt Datenblatt

Empfohlene APBA1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3131021
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3088830
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren APBA1 Produkten

Boyken, Grønborg, Riedel, Urlaub, Jahn, Chua: "Molecular profiling of synaptic vesicle docking sites reveals novel proteins but few differences between glutamatergic and GABAergic synapses." in: Neuron, Vol. 78, Issue 2, pp. 285-97, (2013) (PubMed).

Verlaeten, Casery, Cavagna, Naville, Giraudon, Belin, Begeot, Bernard: "Identification of Urop11, a novel leptin-modulated gene that is upregulated in the hypothalamus of mice with virus-induced obesity." in: Journal of molecular endocrinology, Vol. 38, Issue 1-2, pp. 3-17, (2007) (PubMed).

Jacobs, Williams, Francis: "Cyclin-dependent kinase 5, Munc18a and Munc18-interacting protein 1/X11alpha protein up-regulation in Alzheimer's disease." in: Neuroscience, Vol. 138, Issue 2, pp. 511-22, (2006) (PubMed).

Wong, Setou, Teng, Takei, Hirokawa: "Overexpression of motor protein KIF17 enhances spatial and working memory in transgenic mice." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 22, pp. 14500-5, (2002) (PubMed).

Biederer, Südhof: "Mints as adaptors. Direct binding to neurexins and recruitment of munc18." in: The Journal of biological chemistry, Vol. 275, Issue 51, pp. 39803-6, (2001) (PubMed).

Fisher, Pevsner, Burgoyne: "Control of fusion pore dynamics during exocytosis by Munc18." in: Science (New York, N.Y.), Vol. 291, Issue 5505, pp. 875-8, (2001) (PubMed).

Okamoto, Südhof: "Mints, Munc18-interacting proteins in synaptic vesicle exocytosis." in: The Journal of biological chemistry, Vol. 272, Issue 50, pp. 31459-64, (1998) (PubMed).

Synonyme und alternative Namen zu APBA1

amyloid beta precursor protein binding family A member 1 (APBA1), amyloid beta (A4) precursor protein-binding, family A, member 1b (apba1b), ketopantoate reductase (apbA1), 2-dehydropantoate 2-reductase (apbA1), 2-dehydropantoate 2-reductase (apba1), amyloid beta (A4) precursor protein-binding, family A, member 1 (X11) (apba1), amyloid beta (A4) precursor protein-binding, family A, member 1 (apba1), amyloid beta (A4) precursor protein binding, family A, member 1 (Apba1), amyloid beta precursor protein binding family A member 1 (Apba1), 6430513E09Rik, APBA1, D9S411E, Lin-10, LIN10, Mint, Mint1, MINT1, Urop11, X11, X11A, X11alpha, X11ALPHA

Bezeichner auf Proteinebene für APBA1

  • amyloid beta (A4) precursor protein-binding, family A, member 1
  • amyloid beta A4 precursor protein-binding, family A, member 1
  • amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
  • ketopantoate reductase
  • 2-dehydropantoate 2-reductase
  • Amyloid beta A4 precursor protein-binding family A member 1
  • amyloid beta A4 precursor protein-binding family A member 1-like
  • UROP11-110
  • adapter protein X11alpha
  • amyloid beta A4 precursor protein-binding family A member 1
  • mint-1
  • neuron-specific X11 protein
  • neuronal Munc18-1-interacting protein 1
  • amyloid beta (A4) precursor protein-binding family A APBA1: amyloid beta (A4) precursor protein-binding family A member 1 (X11)
  • amyloid beta (A4) precursor protein-binding, family A, APBA1: amyloid beta (A4) precursor protein-binding, family A, member 1 (X11)
  • adaptor protein X11alpha
  • neuronal munc18-1-interacting protein 1
  • phosphotyrosine-binding/-interacting domain (PTB)-bearing protein
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