APLP2 Produkte
(Amyloid beta (A4) Precursor-Like Protein 2 (APLP2))
Kategorien
This gene encodes amyloid precursor- like protein 2 (APLP2), which is a member of the APP (amyloid precursor protein) family including APP, APLP1 and APLP2. This protein is ubiquitously expressed. It contains heparin-, copper- and zinc- binding domains at the N-terminus, BPTI/Kunitz inhibitor and E2 domains in the middle region, and transmembrane and intracellular domains at the C-terminus. This protein interacts with major histocompatibility complex (MHC) class I molecules. The synergy of this protein and the APP is required to mediate neuromuscular transmission, spatial learning and synaptic plasticity. This protein has been implicated in the pathogenesis of Alzheimer's disease. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011].
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Ausgewählte APLP2 Kategorien
APLP2 Antikörper
High quality antibodies with extensive validation data.
APLP2 ELISA Kits
Reliable ELISA kits for a wide range of species.
APLP2 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene APLP2 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p)
Validierungen
- (4)
Kat. Nr.
ABIN2855243
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IP, ICC
Validierungen
- (3)
Kat. Nr.
ABIN7426694
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
IHC, ELISA
Validierungen
- (2)
Kat. Nr.
ABIN7144051
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene APLP2 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964811
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953687
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validierungen
Kat. Nr.
ABIN1380928
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene APLP2 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (2)
Kat. Nr.
ABIN7273823
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345324
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345326
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren APLP2 Produkten
: "The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice." in: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, Vol. 35, Issue 4, pp. 655-66, (2015) (PubMed).: "Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other." in: The Journal of biological chemistry, Vol. 290, Issue 30, pp. 18609-20, (2015) (PubMed).
: "Abnormal platelet amyloid-? protein precursor (A?PP) metabolism in Alzheimer's disease: identification and characterization of a new A?PP isoform as potential biomarker." in: Journal of Alzheimer's disease : JAD, Vol. 35, Issue 2, pp. 285-95, (2013) (PubMed).
: "Amyloid precursor-like protein 2 increases the endocytosis, instability, and turnover of the H2-K(d) MHC class I molecule." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 181, Issue 3, pp. 1978-87, (2008) (PubMed).
Synonyme und alternative Namen zu APLP2
suppression of tumorigenicity 14 (ST14), amyloid beta precursor like protein 2 (APLP2), amyloid beta (A4) precursor-like protein 2 (Aplp2), amyloid beta precursor like protein 2 (Aplp2), amyloid beta (A4) precursor-like protein 2 S homeolog (aplp2.S), amyloid beta (A4) precursor-like protein 2 (aplp2), amyloid beta (A4) precursor-like protein 2 L homeolog (aplp2.L), amyloid beta precursor like protein 2 (aplp2), AI790698, APLP-2, APLP2, aplp2 A, aplp2 B, APPH, Apph, APPL2, CDEBP, HAI, MGC86389, MT-SP1, MTSP1, PRSS14, si:dkey-11k4.3, SNC19, TADG15, TMPRSS14, WALPLP2Bezeichner auf Proteinebene für APLP2
- membrane-type serine protease 1
- prostamin
- serine protease 14
- serine protease TADG-15
- suppression of tumorigenicity 14 (colon carcinoma, matriptase, epithin)
- suppressor of tumorigenicity 14 protein
- tumor associated differentially expressed gene 15 protein
- tumor-associated differentially-expressed gene 15 protein
- CDEI box-binding protein
- amyloid precursor protein homolog HSD-2
- amyloid-like protein 2
- CDEBP
- Amyloid protein precursor-like protein 2
- amyloid beta (A4) precursor-like protein 2-like
- sperm membrane protein (YWK-II)
- sperm membrane protein YWK-II
- amyloid beta (A4) precursor-like protein 2
- amyloid-beta-like protein B
- suppression of tumorigenicity 14
- amyloid-like protein 2-like
- amyloid-beta-like protein A
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