APOBEC3A and APOBEC3B Deletion Hybrid Antikörper
(APOBEC3A and APOBEC3B Deletion Hybrid (APOBEC3A_B))
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. The protein encoded by this gene lacks the zinc binding activity of other family members. The protein plays a role in immunity, by restricting transmission of foreign DNA such as viruses. One mechanism of foreign DNA restriction is deamination of foreign double-stranded DNA cytidines to uridines, which leads to DNA degradation. However, other mechanisms are also thought to be involved, as anti-viral effect is not dependent on deaminase activity. The protein encoded by this gene is the same as that encoded by APOBEC3A; however, this gene is a hybrid gene that results from the deletion of approximately 29.5 kb of sequence between the APOBEC3A gene and the adjacent gene APOBEC3B. The breakpoints of the deletion are within the two genes, so the deletion hybrid is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. [provided by RefSeq, Jul 2012].
antibodies-online.com steht für hochwertige Forschungsprodukte. Suchen, finden und bestellen Sie Tools mit umfangreichen Validierungsdaten, Bildern, Referenzen. Unser wissenschaftlicher Kundenservice steht Ihnen jederzeit zur Verfügung, wenn Sie Fragen zur Auswahl oder Anwendung unserer Produkte haben.
Ausgewählte APOBEC3A and APOBEC3B Deletion Hybrid Kategorien
APOBEC3A and APOBEC3B Deletion Hybrid Antikörper
High quality antibodies with extensive validation data.
Empfohlene APOBEC3A and APOBEC3B Deletion Hybrid Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, WB
Validierungen
- (1)
Kat. Nr.
ABIN6259985
Menge
100 μL
Datenblatt
Datenblatt
Synonyme und alternative Namen zu APOBEC3A and APOBEC3B Deletion Hybrid
APOBEC3A and APOBEC3B deletion hybrid (APOBEC3A_B), A3ABezeichner auf Proteinebene für APOBEC3A and APOBEC3B Deletion Hybrid
- Phorbolin-1
- probable DNA dC->dU-editing enzyme APOBEC-3A
Sie sind hier:
