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APP Produkte

(Amyloid beta (A4) Precursor Protein (APP))
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte APP Kategorien

APP Antikörper

High quality antibodies with extensive validation data.

APP ELISA Kits

Reliable ELISA kits for a wide range of species.

APP Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene APP Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC, IHC (fro)
Validierungen
  • (7)
  • (1)
Kat. Nr. ABIN2855011
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN3020680
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse, Rat
Applikation WB, IF
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN197432
Menge 0.1 mL
Datenblatt Datenblatt

Empfohlene APP ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (2)
  • (1)
Kat. Nr. ABIN6953681
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6999550
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953682
Menge 96 tests
Datenblatt Datenblatt

Empfohlene APP Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345399
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345401
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (1)
Kat. Nr. ABIN7092740
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren APP Produkten

Wang, Xie, Yu, Fang, Zhu, Cheng, Gu, Wang, Xiao: "Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity." in: Scientific reports, Vol. 7, Issue 1, pp. 7497, (2019) (PubMed).

Wen, You, Wang, Meng, Feng, Yang: "Polarization of Microglia to the M2 Phenotype in a Peroxisome Proliferator-Activated Receptor Gamma-Dependent Manner Attenuates Axonal Injury Induced by Traumatic Brain Injury in Mice." in: Journal of neurotrauma, (2018) (PubMed).

Liu, Sun, Wan, Jiang, Bo, Lin, Tang, Xu: "β-Sheet Breaker Peptide-HPYD for the Treatment of Alzheimer's Disease: Primary Studies on Behavioral Test and Transcriptional Profiling." in: Frontiers in pharmacology, Vol. 8, pp. 969, (2018) (PubMed).

Yang, Han, Luo, Hu, Xu, Li, Hu, Huang, Ma, Yang, Chen, Li, Zhang, Xia, Chen, Wang, Ran, Yang: "Adapentpronitrile, a New Dipeptidyl Peptidase-IV Inhibitor, Ameliorates Diabetic Neuronal Injury Through Inhibiting Mitochondria-Related Oxidative Stress and Apoptosis." in: Frontiers in cellular neuroscience, Vol. 12, pp. 214, (2018) (PubMed).

Dursun, Gezen-Ak: "Vitamin D receptor is present on the neuronal plasma membrane and is co-localized with amyloid precursor protein, ADAM10 or Nicastrin." in: PLoS ONE, Vol. 12, Issue 11, pp. e0188605, (2017) (PubMed).

Yu, Wang, Mu, Ding, Ding: "Effect of general anesthesia on serum β-amyloid protein and regional cerebral oxygen saturation of elderly patients after subtotal gastrectomy." in: Experimental and therapeutic medicine, Vol. 12, Issue 6, pp. 3561-3566, (2017) (PubMed).

Potter, Potter: "Molecular Anatomy of Palate Development." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132662, (2015) (PubMed).

Wang, Wang: "Studying the relationship between cell cycle and Alzheimer's disease by gold nanoparticle probes." in: Analytical biochemistry, Vol. 489, pp. 32-7, (2015) (PubMed).

Planque, Nishiyama, Sonoda, Lin, Taguchi, Hara, Kolodziej, Mitsuda, Gonzalez, Sait, Fukuchi, Massey, Friedland, ONuallain, Sigurdsson, Paul: "Specific amyloid β clearance by a catalytic antibody construct." in: The Journal of biological chemistry, Vol. 290, Issue 16, pp. 10229-41, (2015) (PubMed).

Song, Li, Lin, Cao: "Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimer's disease via mammalian target of rapamycin-dependent and -independent pathways." in: Molecular medicine reports, Vol. 12, Issue 5, pp. 7615-22, (2015) (PubMed).

Synonyme und alternative Namen zu APP

amyloid beta precursor protein (APP), amyloid beta (A4) precursor protein (APP), amyloid beta precursor protein (app), beta amyloid protein precursor-like (Appl), amyloid beta precursor protein (App), amyloid beta (A4) precursor protein (App), amyloid beta (A4) precursor protein a (appa), amyloid beta precursor protein L homeolog (app.L), AAA, aaa, ABETA, abeta, Abeta, ABPP, abpp, Abpp, AD1, ad1, Adap, Ag, APP, app, APP-like, APPI, appi, APPL, appl, BcDNA:GH04413, betaApp, CG7727, CTFgamma, ctfgamma, CVAP, cvap, Cvap, Dmel\\CG7727, E030013M08Rik, EG:65F1.5, PN-II, PN2, pn2, wu:fj34d10, wu:fk65e12, zgc:85740

Bezeichner auf Proteinebene für APP

  • alzheimer disease amyloid protein
  • amyloid beta A4 protein
  • beta-amyloid peptide
  • cerebral vascular amyloid peptide
  • peptidase nexin-II
  • preA4
  • protease nexin-II
  • amyloid protein
  • ABPP
  • alzheimer disease amyloid A4 protein homolog
  • amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
  • Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimers disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4)
  • amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease)
  • amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease)
  • beta-amyloid precursor protein
  • Appl-PA
  • Appl-PB
  • Appl-PC
  • Appl-PD
  • Appl-PE
  • Appl-PF
  • CG7727-PA
  • CG7727-PB
  • CG7727-PC
  • CG7727-PD
  • CG7727-PE
  • CG7727-PF
  • amyloid precursor protein
  • amyloid precursor protein-like
  • beta-amyloid-protein-precursor-like
  • AG
  • amyloid A4
  • amyloidogenic glycoprotein
  • appican
  • protease nexin II
  • amyloid beta precursor protein a
  • beta-amyloid precursor protein A
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