APP Produkte
(Amyloid beta (A4) Precursor Protein (APP))
Kategorien
This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Ausgewählte APP Kategorien
APP Antikörper
High quality antibodies with extensive validation data.
APP ELISA Kits
Reliable ELISA kits for a wide range of species.
APP Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene APP Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC, IHC (fro)
Validierungen
- (7)
- (1)
Kat. Nr.
ABIN2855011
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC
Validierungen
- (4)
- (1)
Kat. Nr.
ABIN3020680
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IF
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN197432
Menge
0.1 mL
Datenblatt
Datenblatt
Empfohlene APP ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (2)
- (1)
Kat. Nr.
ABIN6953681
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6999550
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953682
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene APP Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345399
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345401
Menge
25 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
Kat. Nr.
ABIN7092740
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren APP Produkten
: "Amyloid aggregates induced by the p53-R280T mutation lead to loss of p53 function in nasopharyngeal carcinoma." in: Cell death & disease, Vol. 15, Issue 1, pp. 35, (2024) (PubMed).: "Aβ∗56 is a stable oligomer that impairs memory function in mice." in: iScience, Vol. 27, Issue 3, pp. 109239, (2024) (PubMed).
: "The divergent effects of astrocyte ceruloplasmin on learning and memory function in young and old mice." in: Cell death & disease, Vol. 13, Issue 11, pp. 1006, (2022) (PubMed).
: "Plasmonic nanoparticle amyloid corona for screening Aβ oligomeric aggregate-degrading drugs." in: Nature communications, Vol. 12, Issue 1, pp. 639, (2021) (PubMed).
: "Iron potentiates microglial interleukin-1β secretion induced by amyloid-β." in: Journal of neurochemistry, Vol. 154, Issue 2, pp. 177-189, (2020) (PubMed).
: "Cerebrovascular miRNAs correlate with the clearance of Aβ through perivascular route in younger 3xTg-AD mice." in: Brain pathology (Zurich, Switzerland), Vol. 30, Issue 1, pp. 92-105, (2020) (PubMed).
: "Involvement of Insulin Signaling Disturbances in Bisphenol A-Induced Alzheimer's Disease-like Neurotoxicity." in: Scientific reports, Vol. 7, Issue 1, pp. 7497, (2019) (PubMed).
: "Multifunctionalized Reduced Graphene Oxide Biosensors for Simultaneous Monitoring of Structural Changes in Amyloid-β 40." in: Sensors (Basel, Switzerland), Vol. 18, Issue 6, (2018) (PubMed).
: "Polarization of Microglia to the M2 Phenotype in a Peroxisome Proliferator-Activated Receptor Gamma-Dependent Manner Attenuates Axonal Injury Induced by Traumatic Brain Injury in Mice." in: Journal of neurotrauma, (2018) (PubMed).
: "β-Sheet Breaker Peptide-HPYD for the Treatment of Alzheimer's Disease: Primary Studies on Behavioral Test and Transcriptional Profiling." in: Frontiers in pharmacology, Vol. 8, pp. 969, (2018) (PubMed).
Synonyme und alternative Namen zu APP
amyloid beta precursor protein (APP), amyloid beta (A4) precursor protein (APP), amyloid beta precursor protein (app), beta amyloid protein precursor-like (Appl), amyloid beta precursor protein (App), amyloid beta (A4) precursor protein (App), amyloid beta (A4) precursor protein a (appa), amyloid beta precursor protein L homeolog (app.L), AAA, aaa, ABETA, abeta, Abeta, ABPP, abpp, Abpp, AD1, ad1, Adap, Ag, APP, app, APP-like, APPI, appi, APPL, appl, BcDNA:GH04413, betaApp, CG7727, CTFgamma, ctfgamma, CVAP, cvap, Cvap, Dmel\\CG7727, E030013M08Rik, EG:65F1.5, PN-II, PN2, pn2, wu:fj34d10, wu:fk65e12, zgc:85740Bezeichner auf Proteinebene für APP
- alzheimer disease amyloid protein
- amyloid beta A4 protein
- beta-amyloid peptide
- cerebral vascular amyloid peptide
- peptidase nexin-II
- preA4
- protease nexin-II
- amyloid protein
- ABPP
- alzheimer disease amyloid A4 protein homolog
- amyloid beta (A4) precursor protein (peptidase nexin-II, Alzheimer disease)
- Amyloid beta A4 protein precursor (APP) (ABPP) (Alzheimers disease amyloid protein) (Cerebral vascular amyloid peptide) (CVAP) (Protease nexin-II) (PN-II) (APPI) (PreA4)
- amyloid beta (A4) precursor protein (peptidase nexin-2, Alzheimer disease)
- amyloid beta (A4) precursor protein (protease nexin-II, Alzheimer disease)
- beta-amyloid precursor protein
- Appl-PA
- Appl-PB
- Appl-PC
- Appl-PD
- Appl-PE
- Appl-PF
- CG7727-PA
- CG7727-PB
- CG7727-PC
- CG7727-PD
- CG7727-PE
- CG7727-PF
- amyloid precursor protein
- amyloid precursor protein-like
- beta-amyloid-protein-precursor-like
- AG
- amyloid A4
- amyloidogenic glycoprotein
- appican
- protease nexin II
- amyloid beta precursor protein a
- beta-amyloid precursor protein A
Haben Sie etwas anderes gesucht?
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- Apoptotic Neutrophils
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- Apoptosis Inhibitor 5
- APOPT1
- Apoprotein A1
- APOOL
- Apolipoprotein O
- Apolipoprotein M
- Apolipoprotein L 5
- Apolipoprotein L 4
- Apolipoprotein L 2
- Apolipoprotein F
- Apolipoprotein D
- Apolipoprotein C-II
- Apolipoprotein A-I
- Apolipoprotein A
- APOLD1
- APOL6
- APOL3
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