ARNT Produkte
(Aryl Hydrocarbon Receptor Nuclear Translocator (ARNT))
Kategorien
The aryl hydrocarbon (Ah) receptor is involved in the induction of several enzymes that participate in xenobiotic metabolism. The ligand-free, cytosolic form of the Ah receptor is complexed to heat shock protein 90. Binding of ligand, which includes dioxin and polycyclic aromatic hydrocarbons, results in translocation of the ligand-binding subunit only to the nucleus. Induction of enzymes involved in xenobiotic metabolism occurs through binding of the ligand-bound Ah receptor to xenobiotic responsive elements in the promoters of genes for these enzymes. This gene encodes a protein that forms a complex with the ligand-bound Ah receptor, and is required for receptor function. The encoded protein has also been identified as the beta subunit of a heterodimeric transcription factor, hypoxia-inducible factor 1. A t(1\;12)(q21\;p13) translocation, which results in a TEL-ARNT fusion protein, is associated with acute myeloblastic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2010].
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Ausgewählte ARNT Kategorien
ARNT Antikörper
High quality antibodies with extensive validation data.
ARNT ELISA Kits
Reliable ELISA kits for a wide range of species.
ARNT Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ARNT Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, IHC (p), RNAi
Validierungen
- (7)
Kat. Nr.
ABIN559953
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IF
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN513506
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB, IHC, ELISA, IF, ICC
Validierungen
- (4)
Kat. Nr.
ABIN6260045
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene ARNT ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN6953934
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965029
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6953933
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ARNT Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN1345671
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345673
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7397531
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ARNT Produkten
: "Molecular cloning and characterization of two ARNT (ARNT-1 and ARNT-2) genes in Atlantic croaker and their expression during coexposure to hypoxia and PCB77." in: Environmental toxicology, Vol. 34, Issue 2, pp. 160-171, (2019) (PubMed).: "Inherent DNA-binding specificities of the HIF-1α and HIF-2α transcription factors in chromatin." in: EMBO reports, Vol. 20, Issue 1, (2019) (PubMed).
: "MITF controls the TCA cycle to modulate the melanoma hypoxia response." in: Pigment cell & melanoma research, (2019) (PubMed).
: "Chemotherapy induces enrichment of CD47+/CD73+/PDL1+ immune evasive triple-negative breast cancer cells." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, Issue 6, pp. E1239-E1248, (2018) (PubMed).
: "AhR and SHP regulate phosphatidylcholine and S-adenosylmethionine levels in the one-carbon cycle." in: Nature communications, Vol. 9, Issue 1, pp. 540, (2018) (PubMed).
: "NF-κB-Dependent Lymphoid Enhancer Co-option Promotes Renal Carcinoma Metastasis." in: Cancer discovery, Vol. 8, Issue 7, pp. 850-865, (2018) (PubMed).
: "Anti-inflammatory Effects of Phyllanthus emblica L on Benzopyrene-Induced Precancerous Lung Lesion by Regulating the IL-1β/miR-101/Lin28B Signaling Pathway." in: Integrative cancer therapies, Vol. 16, Issue 4, pp. 505-515, (2018) (PubMed).
: "Metastasis-Associated Protein 1 Deficiency Results in Compromised Pulmonary Alveolar Capillary Angiogenesis in Mice." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 3932-3941, (2018) (PubMed).
: "TLR4 promotes the expression of HIF-1α by triggering reactive oxygen species in cervical cancer cells in vitro-implications for therapeutic intervention." in: Molecular medicine reports, Vol. 17, Issue 2, pp. 2229-2238, (2018) (PubMed).
: "Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer." in: Cell reports, Vol. 25, Issue 13, pp. 3721-3732.e6, (2018) (PubMed).
Synonyme und alternative Namen zu ARNT
aryl hydrocarbon receptor nuclear translocator (ARNT), aryl hydrocarbon receptor nuclear translocator (Arnt), aryl hydrocarbon receptor nuclear translocator (arnt), aryl hydrocarbon receptor nuclear translocator S homeolog (arnt.S), ARNT, arnt.2, Arnt1, arnt1, bHLHe2, D3Ertd557e, Drnt, ESTM42, HIF-1-beta, HIF-1beta, hif-1beta, HIF1-beta, HIF1B, Hif1b, hif1b, HIF1BETA, hif1beta, MGC68805, mKIAA4051, TANGO, tango, W08714, xArnt, zgc:136664Bezeichner auf Proteinebene für ARNT
- class E basic helix-loop-helix protein 2
- dioxin receptor, nuclear translocator
- hypoxia-inducible factor 1, beta subunit
- ARNT protein
- HIF-1 beta
- HIF-1-beta
- HIF1-beta
- aryl hydrocarbon receptor nuclear translocator
- hypoxia-inducible factor 1 beta
- hypoxia-inducible factor 1-beta
- Aryl hydrocarbon receptor nuclear translocator 1
- ARNT1
- aryl hydrocarbon receptor nuclear translocater
- aryl hydrocarbon receptor nuclear translocator 2
- rtARNT
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