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ASAP1 Produkte

(ArfGAP with SH3 Domain, Ankyrin Repeat and PH Domain 1 (ASAP1))
This gene encodes an ADP-ribosylation factor (ARF) GTPase-activating protein. The GTPase-activating activity is stimulated by phosphatidylinositol 4,5-biphosphate (PIP2), and is greater towards ARF1 and ARF5, and lesser for ARF6. This gene maybe involved in regulation of membrane trafficking and cytoskeleton remodeling. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011].

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Ausgewählte ASAP1 Kategorien

ASAP1 Antikörper

High quality antibodies with extensive validation data.

ASAP1 ELISA Kits

Reliable ELISA kits for a wide range of species.

ASAP1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ASAP1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF
Validierungen
  • (5)
Kat. Nr. ABIN565496
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validierungen
  • (2)
Kat. Nr. ABIN753703
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, ELISA, IHC
Validierungen
  • (1)
  • (1)
Kat. Nr. ABIN129669
Menge 100 μg
Datenblatt Datenblatt

Empfohlene ASAP1 ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6971241
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ASAP1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345785
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3089560
Menge 1 mg
Datenblatt Datenblatt
Reaktivität Mouse
Source Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr. ABIN3137365
Menge 1 mg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ASAP1 Produkten

Schreiber, Saraswati, Harkins, Gruber, Cremers, Thiele, Rothley, Plaumann, Korn, Armant, Augustin, Sleeman: "Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling." in: PLoS genetics, Vol. 15, Issue 6, pp. e1008216, (2019) (PubMed).

Bender, Stritt, Nurden, van Eeuwijk, Zieger, Kentouche, Schulze, Morbach, Stegner, Heinze, Heinze, Dütting, Gupta, Witke, Falet, Fischer, Hartwig, Nieswandt: "Megakaryocyte-specific Profilin1-deficiency alters microtubule stability and causes a Wiskott-Aldrich syndrome-like platelet defect." in: Nature communications, Vol. 5, pp. 4746, (2015) (PubMed).

Sato, Zhao, Imai, Simister, Feller, Trackman, Kirsch, Sonenshein: "Inhibition of CIN85-mediated invasion by a novel SH3 domain binding motif in the lysyl oxidase propeptide." in: PLoS ONE, Vol. 8, Issue 10, pp. e77288, (2013) (PubMed).

Matsui, Kaieda, Ikegami, Mimori-Kiyosue: "Identification of a link between the SAMP repeats of adenomatous polyposis coli tumor suppressor and the Src homology 3 domain of DDEF." in: The Journal of biological chemistry, Vol. 283, Issue 47, pp. 33006-20, (2008) (PubMed).

Liu, Yerushalmi, Grigera, Parsons: "Mislocalization or reduced expression of Arf GTPase-activating protein ASAP1 inhibits cell spreading and migration by influencing Arf1 GTPase cycling." in: The Journal of biological chemistry, Vol. 280, Issue 10, pp. 8884-92, (2005) (PubMed).

Kruljac-Letunic, Moelleken, Kallin, Wieland, Blaukat: "The tyrosine kinase Pyk2 regulates Arf1 activity by phosphorylation and inhibition of the Arf-GTPase-activating protein ASAP1." in: The Journal of biological chemistry, Vol. 278, Issue 32, pp. 29560-70, (2003) (PubMed).

Liu, Loijens, Martin, Karginov, Parsons: "The association of ASAP1, an ADP ribosylation factor-GTPase activating protein, with focal adhesion kinase contributes to the process of focal adhesion assembly." in: Molecular biology of the cell, Vol. 13, Issue 6, pp. 2147-56, (2002) (PubMed).

Synonyme und alternative Namen zu ASAP1

ArfGAP with SH3 domain, ankyrin repeat and PH domain1 (Asap1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (ASAP1), toxic extracellular endopeptidase (asaP1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (Asap1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 (asap1), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 L homeolog (asap1.L), ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a (asap1a), AMAP1, ASAP1, Asap1, AV239055, CENTB4, Ddef1, DDEF1, ddef1, DEF-1, mKIAA1249, PAG2, PAP, s19, si:ch211-160i2.3, ZG14P

Bezeichner auf Proteinebene für ASAP1

  • 130 kDa phosphatidylinositol 4,5-biphosphate-dependent ARF1 GTPase-activating protein
  • 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein
  • ADP-ribosylation factor-directed GTPase-activating protein 1
  • ARF GTPase-activating protein 1
  • PIP2-dependent ARF1 GAP
  • arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
  • development and differentiation-enhancing factor 1
  • DEF-1
  • centaurin, beta 4
  • development and differentiation enhancing factor 1
  • differentiation-enhancing factor 1
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
  • arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1-like
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain1
  • ArfGAP with SH3 domain, ankyrin repeat and PH domain 1a
  • arfGAP with SH3 domain, ankyrin repeat and PH domain 1a
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