ASL Produkte
(Argininosuccinate Lyase (ASL))
Kategorien
This gene encodes a member of the lyase 1 family. The encoded protein forms a cytosolic homotetramer and primarily catalyzes the reversible hydrolytic cleavage of argininosuccinate into arginine and fumarate, an essential step in the liver in detoxifying ammonia via the urea cycle. Mutations in this gene result in the autosomal recessive disorder argininosuccinic aciduria, or argininosuccinic acid lyase deficiency. A nontranscribed pseudogene is also located on the long arm of chromosome 22. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008].
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Ausgewählte ASL Kategorien
ASL Antikörper
High quality antibodies with extensive validation data.
ASL ELISA Kits
Reliable ELISA kits for a wide range of species.
ASL Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ASL Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IF, IHC (p), ICC
Validierungen
- (1)
- (6)
Kat. Nr.
ABIN2856924
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (5)
Kat. Nr.
ABIN6137201
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
ELISA, IHC, IF
Validierungen
- (3)
Kat. Nr.
ABIN7144595
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene ASL ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Validierungen
Kat. Nr.
ABIN1122449
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Mouse
Analytical Method
Validierungen
Kat. Nr.
ABIN1122450
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Validierungen
Kat. Nr.
ABIN1122451
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ASL Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345857
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121890
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN2128038
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ASL Produkten
: "Argininosuccinate lyase interacts with cyclin A2 in cytoplasm and modulates growth of liver tumor cells." in: Oncology reports, Vol. 37, Issue 2, pp. 969-978, (2017) (PubMed).: "Argininosuccinate lyase is a potential therapeutic target in breast cancer." in: Oncology reports, Vol. 34, Issue 6, pp. 3131-9, (2015) (PubMed).
: "Quantitative liver-specific protein fingerprint in blood: a signature for hepatotoxicity." in: Theranostics, Vol. 4, Issue 2, pp. 215-28, (2014) (PubMed).
: "Epigenetic status of argininosuccinate synthetase and argininosuccinate lyase modulates autophagy and cell death in glioblastoma." in: Cell death & disease, Vol. 4, pp. e458, (2013) (PubMed).
: "Understanding the role of argininosuccinate lyase transcript variants in the clinical and biochemical variability of the urea cycle disorder argininosuccinic aciduria." in: The Journal of biological chemistry, Vol. 288, Issue 48, pp. 34599-611, (2013) (PubMed).
: "Argininosuccinate lyase deficiency: mutational spectrum in Italian patients and identification of a novel ASL pseudogene." in: Human mutation, Vol. 28, Issue 7, pp. 694-702, (2007) (PubMed).
: "A novel stop codon mutation (X465Y) in the argininosuccinate lyase gene in a patient with argininosuccinic aciduria." in: The Tohoku journal of experimental medicine, Vol. 198, Issue 2, pp. 119-24, (2003) (PubMed).
Synonyme und alternative Namen zu ASL
argininosuccinate lyase (ASL), argininosuccinate lyase (Asl), argininosuccinate lyase (asl), argininosuccinate lyase (argH2), argininosuccinate lyase ArgH (argH), argininosuccinate lyase (argH), argininosuccinate lyase (arg7), argininosuccinate lyase (CNC04420), argininosuccinate lyase (STHERM_c13370), adenylosuccinate lyase (Adsl), argininosuccinate lyase L homeolog (asl.L), argininosuccinate lyase (ARG7), 2510006M18Rik, Adl, ASAL, Asl, BA4879, PSPTO0125, zgc:63532Bezeichner auf Proteinebene für ASL
- argininosuccinase
- arginosuccinase
- ASAL
- argininosuccinate lyase
- ASase
- adenylosuccinase
- adenylosuccinate lyase 1
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