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ASXL1 Produkte

(Additional Sex Combs Like 1 (ASXL1))
This gene is similar to the Drosophila additional sex combs gene, which encodes a chromatin-binding protein required for normal determination of segment identity in the developing embryo. The protein is a member of the Polycomb group of proteins, which are necessary for the maintenance of stable repression of homeotic and other loci. The protein is thought to disrupt chromatin in localized areas, enhancing transcription of certain genes while repressing the transcription of other genes. The protein encoded by this gene functions as a ligand-dependent co-activator for retinoic acid receptor in cooperation with nuclear receptor coactivator 1. Mutations in this gene are associated with myelodysplastic syndromes and chronic myelomonocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009].

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Ausgewählte ASXL1 Kategorien

ASXL1 Antikörper

High quality antibodies with extensive validation data.

ASXL1 Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ASXL1 Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (5)
Kat. Nr. ABIN949894
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Mouse
Applikation WB, FACS, IF, IHC (p)
Validierungen
  • (4)
Kat. Nr. ABIN655084
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, FACS, IF, IHC (p), EIA
Validierungen
  • (4)
Kat. Nr. ABIN950543
Menge 0.4 mL
Datenblatt Datenblatt

Empfohlene ASXL1 Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN7121702
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345902
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN1692425
Menge 50 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ASXL1 Produkten

Balasubramani, Larjo, Bassein, Chang, Hastie, Togher, Lähdesmäki, Rao: "Cancer-associated ASXL1 mutations may act as gain-of-function mutations of the ASXL1-BAP1 complex." in: Nature communications, Vol. 6, pp. 7307, (2015) (PubMed).

Davies, Yip, Fernandez-Mercado, Woll, Agirre, Prosper, Jacobsen, Wainscoat, Pellagatti, Boultwood: "Silencing of ASXL1 impairs the granulomonocytic lineage potential of human CD34? progenitor cells." in: British journal of haematology, Vol. 160, Issue 6, pp. 842-50, (2013) (PubMed).

Fisher, Berger, Randazzo, Brock: "A human homolog of Additional sex combs, ADDITIONAL SEX COMBS-LIKE 1, maps to chromosome 20q11." in: Gene, Vol. 306, pp. 115-26, (2003) (PubMed).

Synonyme und alternative Namen zu ASXL1

additional sex combs like 1, transcriptional regulator L homeolog (asxl1.L), additional sex combs like 1, transcriptional regulator (ASXL1), additional sex combs like 1, transcriptional regulator (asxl1), additional sex combs like 1 (Asxl1), asxl1, BOPS, MDS, MGC83850, mKIAA0978

Bezeichner auf Proteinebene für ASXL1

  • additional sex combs like 1
  • additional sex combs-like protein 1
  • putative Polycomb group protein ASXL1
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