ATF6 Produkte
(Activating Transcription Factor 6 (ATF6))
Kategorien
This gene encodes a transcription factor that activates target genes for the unfolded protein response (UPR) during endoplasmic reticulum (ER) stress. Although it is a transcription factor, this protein is unusual in that it is synthesized as a transmembrane protein that is embedded in the ER. It functions as an ER stress sensor/transducer, and following ER stress-induced proteolysis, it functions as a nuclear transcription factor via a cis-acting ER stress response element (ERSE) that is present in the promoters of genes encoding ER chaperones. This protein has been identified as a survival factor for quiescent but not proliferative squamous carcinoma cells. There have been conflicting reports about the association of polymorphisms in this gene with diabetes in different populations, but another polymorphism has been associated with increased plasma cholesterol levels. This gene is also thought to be a potential therapeutic target for cystic fibrosis. [provided by RefSeq, Aug 2011].
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Ausgewählte ATF6 Kategorien
ATF6 Antikörper
High quality antibodies with extensive validation data.
ATF6 ELISA Kits
Reliable ELISA kits for a wide range of species.
ATF6 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ATF6 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
WB, IHC, IF
Validierungen
- (3)
- (9)
Kat. Nr.
ABIN1512605
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Mouse
Applikation
WB, IHC, IP, ICC
Validierungen
- (5)
Kat. Nr.
ABIN7440587
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, IHC (p), FACS
Validierungen
- (1)
- (4)
Kat. Nr.
ABIN652625
Menge
400 μL
Datenblatt
Datenblatt
Empfohlene ATF6 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964572
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Rat
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6964573
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6962051
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene ATF6 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121670
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345944
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1345942
Menge
10 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ATF6 Produkten
: "Ebola Virus Activates IRE1α-Dependent XBP1u Splicing." in: Viruses, Vol. 15, Issue 1, (2023) (PubMed).: "Counteracting Cisplatin-Induced Testicular Damages by Natural Polyphenol Constituent Honokiol." in: Antioxidants (Basel, Switzerland), Vol. 9, Issue 8, (2020) (PubMed).
: "Loss of Calreticulin Uncovers a Critical Role for Calcium in Regulating Cellular Lipid Homeostasis." in: Scientific reports, Vol. 7, Issue 1, pp. 5941, (2019) (PubMed).
: "EMC3 coordinates surfactant protein and lipid homeostasis required for respiration." in: The Journal of clinical investigation, Vol. 127, Issue 12, pp. 4314-4325, (2019) (PubMed).
: "Expressions of ATF6, XBP1, and GRP78 in normal tissue, atypical adenomatous hyperplasia, and adenocarcinoma of the lung." in: Human pathology, Vol. 83, pp. 22-28, (2019) (PubMed).
: "IL-6 mediates ER expansion during hyperpolarization of alternatively activated macrophages." in: Immunology and cell biology, Vol. 97, Issue 2, pp. 203-217, (2019) (PubMed).
: "Imatinib‑induced apoptosis of gastric cancer cells is mediated by endoplasmic reticulum stress." in: Oncology reports, Vol. 41, Issue 3, pp. 1616-1626, (2019) (PubMed).
: "The effect of Tmem135 overexpression on the mouse heart." in: PLoS ONE, Vol. 13, Issue 8, pp. e0201986, (2019) (PubMed).
: "Tauroursodeoxycholic acid attenuates cyclosporine-induced renal fibrogenesis in the mouse model." in: Biochimica et biophysica acta. General subjects, Vol. 1863, Issue 7, pp. 1210-1216, (2019) (PubMed).
: "C/EBPβ mediates palmitate-induced musclin expression via the regulation of PERK/ATF4 pathways in myotubes." in: American journal of physiology. Endocrinology and metabolism, Vol. 316, Issue 6, pp. E1081-E1092, (2019) (PubMed).
Synonyme und alternative Namen zu ATF6
activating transcription factor 6 (ATF6), uncharacterized LOC412432 (LOC412432), activating transcription factor 6 S homeolog (atf6.S), cyclic AMP-dependent transcription factor ATF-6 alpha (LOC100122162), activating transcription factor 6 (Atf6), 9130025P16Rik, 9630036G24, AA789574, ATF-6-like, ATF6, Atf6, ATF6A, Atf6alpha, ESTM49, GB16435Bezeichner auf Proteinebene für ATF6
- activating transcription factor 6
- cyclic AMP-dependent transcription factor ATF-6 alpha-like
- cAMP-dependent transcription factor ATF-6 alpha
- cyclic AMP-dependent transcription factor ATF-6 alpha
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