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ATM Produkte

(Ataxia Telangiectasia Mutated (ATM))
The protein encoded by this gene belongs to the PI3/PI4-kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates\; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of cell cycle checkpoint signaling pathways that are required for cell response to DNA damage and for genome stability. Mutations in this gene are associated with ataxia telangiectasia, an autosomal recessive disorder. [provided by RefSeq, Aug 2010].

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Ausgewählte ATM Kategorien

ATM Antikörper

High quality antibodies with extensive validation data.

ATM ELISA Kits

Reliable ELISA kits for a wide range of species.

ATM Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ATM Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, ELISA, IP, IF, FACS, FM
Validierungen
  • (126)
  • (12)
Kat. Nr. ABIN6656104
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IHC, ELISA, IP, IF, FACS, ICC
Validierungen
  • (7)
Kat. Nr. ABIN363380
Menge 0.05 mL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (4)
Kat. Nr. ABIN7433537
Menge 100 μL
Datenblatt Datenblatt

Empfohlene ATM ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953956
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953957
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Semi-Quantitative Cell ELISA
Validierungen
Kat. Nr. ABIN5526689
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ATM Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345994
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1345996
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7393904
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ATM Produkten

Pan, Wu, Yeh: "ATM Inhibitor Suppresses Gemcitabine-Resistant BTC Growth in a Polymerase θ Deficiency-Dependent Manner." in: Biomolecules, Vol. 10, Issue 11, (2024) (PubMed).

Li, Gai, Li, Yang, Yu: "DNA-PK participates in pre-rRNA biogenesis independent of DNA double-strand break repair." in: Nucleic acids research, Vol. 52, Issue 11, pp. 6360-6375, (2024) (PubMed).

Xin, Gai, Ma, Li, Li, Yu: "Pre-rRNA Facilitates TopBP1-Mediated DNA Double-Strand Break Response." in: Advanced science (Weinheim, Baden-Wurttemberg, Germany), Vol. 10, Issue 28, pp. e2206931, (2023) (PubMed).

Chen, Li, Iemura, Tanaka: "Oxidative stress induces chromosomal instability through replication stress in fibroblasts from aged mice." in: Journal of cell science, Vol. 136, Issue 11, (2023) (PubMed).

Gritti, Basso, Rinchai, Corigliano, Pivetti, Gaviraghi, Rosano, Mazza, Barozzi, Roncador, Parmigiani, Legube, Parazzoli, Cittaro, Bedognetti, Mondino, Segalla, Tonon: "Loss of ribonuclease DIS3 hampers genome integrity in myeloma by disrupting DNA:RNA hybrid metabolism." in: The EMBO journal, Vol. 41, Issue 22, pp. e108040, (2022) (PubMed).

Wang, Oda, Suzuki, Mitani, Aoki: "Cell cycle-dependent radiosensitivity in mouse zygotes." in: DNA repair, Vol. 117, pp. 103370, (2022) (PubMed).

Montales, Ruis, Lindsay, Michael: "MRN-dependent and independent pathways for recruitment of TOPBP1 to DNA double-strand breaks." in: PloS one, Vol. 17, Issue 8, pp. e0271905, (2022) (PubMed).

Jiang, Li, Schroer, Voisin, Ju, Pacal, Erdmann, Shi, Chung, Deng, Chen, Ciavarra, Datti, Mak, Harrington, Dick, Bader, Bremner, Woo, Zacksenhaus: "Hypophosphorylated pRb knock-in mice exhibit hallmarks of aging and vitamin C-preventable diabetes." in: The EMBO journal, Vol. 41, Issue 4, pp. e106825, (2022) (PubMed).

Ka, Lim, Hwang, Kim, Lee: "IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer." in: Cell reports, Vol. 37, Issue 12, pp. 110138, (2022) (PubMed).

Wang, Lee, Shen, Lin, Wu, Lin, Cheng, Chang, Hung, Cho, Liu, Xia, Ji, Liang, Chiang, Liu, Yao, Hung, Wang: "Evading immune surveillance via tyrosine phosphorylation of nuclear PCNA." in: Cell reports, Vol. 36, Issue 8, pp. 109537, (2022) (PubMed).

Synonyme und alternative Namen zu ATM

telomere fusion (tefu), ATM serine/threonine kinase L homeolog (atm.L), ATM serine/threonine kinase (atm), ATM serine/threonine kinase (ATM), ataxia telangiectasia mutated (atm), ataxia telangiectasia mutated (EDI_100660), ataxia telangiectasia mutated (CpipJ_CPIJ001772), ataxia telangiectasia mutated (BDBG_08252), ataxia telangiectasia mutated (PAAG_02532), ataxia telangiectasia mutated (MCYG_05088), ataxia telangiectasia mutated (VDBG_06833), ataxia telangiectasia mutated (atm) (ACLA_015700), serine/threonine-protein kinase ATM (LOC5565620), ataxia telangiectasia mutated (MGYG_07634), ataxia telangiectasia mutated (PGTG_14279), ATM serine/threonine kinase (Atm), ataxia telangiectasia mutated (Atm), AI256621, at1, AT1, ATA, ATC, ATD, atdc, ATDC, ATE, ATM, Atm, atm, atm/tefu, C030026E19Rik, CG6535, dATM, Dmel\\CG6535, tef, Tefu, tel1, TEL1, telo1, TELO1, Xatm

Bezeichner auf Proteinebene für ATM

  • CG6535-PB
  • ataxia telangiectasia mutated
  • ataxia telengiesctasia mutated
  • ataxia-telangiectasia mutated
  • drosophila ATM
  • tefu-PB
  • chunp9624
  • ataxia telangiectasia mutated (includes complementation groups A, C and D)
  • ataxia telangiectasia mutated protein
  • serine-protein kinase ATM-like
  • ataxia telangiectasia mutated (atm)
  • A-T mutated
  • AT mutated
  • TEL1, telomere maintenance 1, homolog
  • serine-protein kinase ATM
  • Ataxia telangiectasia gene mutated in human beings
  • ataxia telangiectasia mutated homolog
  • A-T mutated homolog
  • ATM (ataxia telangiectasia mutated)
  • ataxia telangiectasia gene mutated in human beings
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