ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Produkte
(ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B (ABCB1B))
Kategorien
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier. [provided by RefSeq, Jul 2008].
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Ausgewählte ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Kategorien
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antikörper
High quality antibodies with extensive validation data.
ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
ELISA, WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validierungen
- (4)
- (4)
Kat. Nr.
ABIN670161
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
ELISA, WB, FACS, IF (cc), IF (p), IHC (fro), IHC (p)
Validierungen
- (1)
Kat. Nr.
ABIN686977
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Plasmodium falciparum
Applikation
ELISA
Validierungen
Kat. Nr.
ABIN7178310
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Mouse
Source
Tobacco (Nicotiana tabacum)
Validierungen
Kat. Nr.
ABIN3132560
Menge
1 mg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN5712796
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Entamoeba histolytica
Source
Yeast
Validierungen
- (1)
Kat. Nr.
ABIN5713190
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B Produkten
: "The impact of insulin on chemotherapeutic sensitivity to 5-fluorouracil in gastric cancer cell lines SGC7901, MKN45 and MKN28." in: Journal of experimental & clinical cancer research : CR, Vol. 34, pp. 64, (2016) (PubMed).: "MicroRNA-186 induces sensitivity of ovarian cancer cells to paclitaxel and cisplatin by targeting ABCB1." in: Journal of ovarian research, Vol. 8, pp. 80, (2016) (PubMed).
: "Chronic inflammation up-regulates P-gp in peripheral mononuclear blood cells via the STAT3/Nf-κb pathway in 2,4,6-trinitrobenzene sulfonic acid-induced colitis mice." in: Scientific reports, Vol. 5, pp. 13558, (2016) (PubMed).
: "Ascites Increases Expression/Function of Multidrug Resistance Proteins in Ovarian Cancer Cells." in: PLoS ONE, Vol. 10, Issue 7, pp. e0131579, (2015) (PubMed).
: "Development of a novel orthotopic non-small cell lung cancer model and therapeutic benefit of 2'-(2-bromohexadecanoyl)-docetaxel conjugate nanoparticles." in: Nanomedicine : nanotechnology, biology, and medicine, Vol. 10, Issue 7, pp. 1497-506, (2014) (PubMed).
: "The expression and significance of P-glycoprotein, lung resistance protein and multidrug resistance-associated protein in gastric cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 28, pp. 144, (2009) (PubMed).
Synonyme und alternative Namen zu ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B
ATP binding cassette subfamily B member 1 (ABCB1), ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b), ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b), ABC20, Abcb1, CD243, CLCS, GP170, mdr, MDR1, Mdr1, Mdr1b, P-GP, Pgy-1, PGY1, Pgy1Bezeichner auf Proteinebene für ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1B
- P-glycoprotein 1
- colchicin sensitivity
- doxorubicin resistance
- multidrug resistance protein 1
- ATP-binding cassette sub-family B member 1
- P glycoprotein 1
- multidrug resistance protein 1B
- ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1)
- ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1)
- ATP-binding cassette, sub-family B (MDR/TAP), member 1B
- ATP-binding cassette, subfamily B, member 1B
- P-glycoprotein/multidrug resistance 1
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