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ATP7A Produkte

(ATPase, Cu++ Transporting, alpha Polypeptide (ATP7A))
This gene encodes a transmembrane protein that functions in copper transport across membranes. This protein is localized to the trans-Golgi network, where it is predicted to supply copper to copper-dependent enzymes in the secretory pathway. It relocalizes to the plasma membrane under conditions of elevated extracellular copper, and functions in the efflux of copper from cells. Mutations in this gene are associated with Menkes disease, X-linked cutis laxa, and occipital horn syndrome. [provided by RefSeq, Oct 2011].

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Ausgewählte ATP7A Kategorien

ATP7A Antikörper

High quality antibodies with extensive validation data.

ATP7A ELISA Kits

Reliable ELISA kits for a wide range of species.

ATP7A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ATP7A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN2485193
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN2485192
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, IF, ICC
Validierungen
  • (4)
Kat. Nr. ABIN2485191
Menge 100 μg
Datenblatt Datenblatt

Empfohlene ATP7A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965087
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method
Validierungen
Kat. Nr. ABIN1127849
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method
Validierungen
Kat. Nr. ABIN1127850
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ATP7A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346155
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7423963
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7423960
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ATP7A Produkten

Wang, Zhu, Zhao, Wang: "miR-133a enhances the sensitivity of Hep-2 cells and vincristine-resistant Hep-2v cells to cisplatin by downregulating ATP7B expression." in: International journal of molecular medicine, Vol. 37, Issue 6, pp. 1636-42, (2016) (PubMed).

Ha, Doguer, Collins: "Knockdown of copper-transporting ATPase 1 (Atp7a) impairs iron flux in fully-differentiated rat (IEC-6) and human (Caco-2) intestinal epithelial cells." in: Metallomics : integrated biometal science, Vol. 8, Issue 9, pp. 963-972, (2016) (PubMed).

Montero-Melendez, Gobbetti, Cooray, Jonassen, Perretti: "Biased agonism as a novel strategy to harness the proresolving properties of melanocortin receptors without eliciting melanogenic effects." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 7, pp. 3381-8, (2015) (PubMed).

White, Kambe, Fulcher, Sachdev, Bush, Fritsche, Lee, Quinn, Petris: "Copper transport into the secretory pathway is regulated by oxygen in macrophages." in: Journal of cell science, Vol. 122, Issue Pt 9, pp. 1315-21, (2009) (PubMed).

White, Lee, Kambe, Fritsche, Petris: "A role for the ATP7A copper-transporting ATPase in macrophage bactericidal activity." in: The Journal of biological chemistry, Vol. 284, Issue 49, pp. 33949-56, (2009) (PubMed).

Setty, Tenza, Sviderskaya, Bennett, Raposo, Marks: "Cell-specific ATP7A transport sustains copper-dependent tyrosinase activity in melanosomes." in: Nature, Vol. 454, Issue 7208, pp. 1142-6, (2008) (PubMed).

Schlief, West, Craig, Holtzman, Gitlin: "Role of the Menkes copper-transporting ATPase in NMDA receptor-mediated neuronal toxicity." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, Issue 40, pp. 14919-24, (2006) (PubMed).

Steveson, Ciccotosto, Ma, Mueller, Mains, Eipper: "Menkes protein contributes to the function of peptidylglycine alpha-amidating monooxygenase." in: Endocrinology, Vol. 144, Issue 1, pp. 188-200, (2002) (PubMed).

Synonyme und alternative Namen zu ATP7A

ATPase copper transporting alpha (ATP7A), ATPase, Cu++ transporting, alpha polypeptide (ATP7A), ATPase, Cu++ transporting, alpha polypeptide (atp7a), P-type ATPase (atp7a), ATP synthase subunit a (LOC100049514), ATPase, Cu++ transporting, alpha polypeptide (Atp7a), ATPase copper transporting alpha (atp7a), copper-transporting ATPase 1 (LOC412379), ATPase copper transporting alpha (Atp7a), ATP7A, Atp7a, atp7a, atpase, Blo, blotchy, br, brindled, cal, DDBDRAFT_0218568, DDBDRAFT_0235190, DDB_0218568, DDB_0235190, DSMAX, DXHXS1608e, I14, kal, MK, MNK, Mnk, Mo, mottled, SMAX3, wu:fc43e01, zgc:153422, zgc:158633

Bezeichner auf Proteinebene für ATP7A

  • ATPase, Cu++ transporting, alpha polypeptide (Menkes syndrome)
  • ATPase, Cu++ transporting, alpha polypeptide
  • Menkes disease ATPase
  • calamity
  • copper-transporting ATPase 1
  • copper-transporting P-type ATPase
  • copper-transporting ATPase
  • ATPase protein
  • kaleidoscope
  • Copper-transporting ATPase 1
  • copper-transporting ATPase 1-like
  • Cu++-transporting P-type ATPase
  • Menkes disease-associated protein
  • copper pump 1
  • Menkes protein
  • menkes disease-associated protein homolog
  • copper transporting ATPase
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