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ATP7B Produkte

(ATPase, Cu++ Transporting, beta Polypeptide (ATP7B))
This gene is a member of the P-type cation transport ATPase family and encodes a protein with several membrane-spanning domains, an ATPase consensus sequence, a hinge domain, a phosphorylation site, and at least 2 putative copper-binding sites. This protein functions as a monomer, exporting copper out of the cells, such as the efflux of hepatic copper into the bile. Alternate transcriptional splice variants, encoding different isoforms with distinct cellular localizations, have been characterized. Mutations in this gene have been associated with Wilson disease (WD). [provided by RefSeq, Jul 2008].

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Ausgewählte ATP7B Kategorien

ATP7B Antikörper

High quality antibodies with extensive validation data.

ATP7B ELISA Kits

Reliable ELISA kits for a wide range of species.

ATP7B Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene ATP7B Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, ICC
Validierungen
  • (8)
Kat. Nr. ABIN7441340
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human, Mouse
Applikation WB, IF, IHC (p), FACS
Validierungen
  • (7)
Kat. Nr. ABIN390398
Menge 400 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA
Validierungen
  • (1)
  • (3)
Kat. Nr. ABIN560009
Menge 100 μg
Datenblatt Datenblatt

Empfohlene ATP7B ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953997
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Mouse
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6953998
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
Kat. Nr. ABIN5652087
Menge 96 tests
Datenblatt Datenblatt

Empfohlene ATP7B Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346157
Menge 10 μg
Datenblatt Datenblatt
Reaktivität Mouse
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7408531
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
Kat. Nr. ABIN7408528
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren ATP7B Produkten

Agarwal, Rustagi, Das, Maiti: "PAMAM dendrimer grafted cellulose paper scaffolds as a novel in vitro 3D liver model for drug screening applications." in: Colloids and surfaces. B, Biointerfaces, Vol. 172, pp. 346-354, (2019) (PubMed).

Han, Wang, Liu, Zhang, Zhang, Li, Sun, Li: "The release and detection of copper ions from ultrasmall theranostic Cu2-xSe nanoparticles." in: Nanoscale, Vol. 11, Issue 24, pp. 11819-11829, (2019) (PubMed).

Nguyen, Chakrabarti, Li, Kalim, Zhang, Zhang, Zheng, Guo: "Rational Targeting of Cdc42 Overcomes Drug Resistance of Multiple Myeloma." in: Frontiers in oncology, Vol. 9, pp. 958, (2019) (PubMed).

Li, Li, Xiao, Wang, James Kang: "The loss of copper is associated with the increase in copper metabolism MURR domain 1 in ischemic hearts of mice." in: Experimental biology and medicine (Maywood, N.J.), Vol. 243, Issue 9, pp. 780-785, (2018) (PubMed).

Su, Shihadih, Cao, Detomasi, Heffern, Jia, Stahl, Chang: "A Modular Ionophore Platform for Liver-Directed Copper Supplementation in Cells and Animals." in: Journal of the American Chemical Society, (2018) (PubMed).

Wang, Zhu, Zhao, Wang: "miR-133a enhances the sensitivity of Hep-2 cells and vincristine-resistant Hep-2v cells to cisplatin by downregulating ATP7B expression." in: International journal of molecular medicine, Vol. 37, Issue 6, pp. 1636-42, (2016) (PubMed).

Zhang, Zhang, Fan, Sun, Liu, Cheng, Li, Xu: "A Chinese herbal Formula, Chang-Wei-Qin, Synergistically Enhances Antitumor Effect of Oxaliplatin." in: Pathology oncology research : POR, Vol. 21, Issue 2, pp. 389-97, (2015) (PubMed).

Chen, Kuo, Pan, Tsou, Yeh, Chang: "Mechanistic basis of a combination D-penicillamine and platinum drugs synergistically inhibits tumor growth in oxaliplatin-resistant human cervical cancer cells in vitro and in vivo." in: Biochemical pharmacology, Vol. 95, Issue 1, pp. 28-37, (2015) (PubMed).

Gu, Yang, Qi, Deng, Zhang, Guo, Huang, Li, Shi, Song, Deng: "Novel ATPase Cu(2+) transporting beta polypeptide mutations in Chinese families with Wilson's disease." in: PLoS ONE, Vol. 8, Issue 7, pp. e66526, (2013) (PubMed).

Katagiri, Nakayama, Rahman, Rahman, Katagiri, Ishibashi, Ishikawa, Iida, Nakayama, Otsuki, Miyazaki: "Is ATP7B a predictive marker in patients with ovarian carcinoma treated with platinum-taxane combination chemotherapy?" in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 23, Issue 1, pp. 60-4, (2012) (PubMed).

Synonyme und alternative Namen zu ATP7B

ATPase copper transporting beta (ATP7B), ATPase, Cu++ transporting, beta polypeptide (Atp7b), ATPase copper transporting beta (Atp7b), ATPase, Cu++ transporting, beta polypeptide (Wilson disease) (atp7b), copper-transporting ATPase 2 (LOC592143), ATPase, Cu++ transporting, beta polypeptide (atp7b), ATPase copper transporting beta (atp7b), Atp7a, ATP7B, Hts, PINA, PWD, tx, WC1, WD, Wd, WND

Bezeichner auf Proteinebene für ATP7B

  • ATPase, Cu(2+)- transporting, beta polypeptide
  • Wilson disease-associated protein
  • copper pump 2
  • copper-transporting ATPase 2
  • Wilson protein
  • toxic milk
  • wilson disease-associated protein homolog
  • ATPase, Cu++ transporting, beta polypeptide (same as Wilson disease)
  • PINA gene, promoter
  • pineal night-specific ATPase
  • ATPase 7B protein
  • ATPase, Cu++ transporting, beta polypeptide (Wilson disease)
  • Wilson's disease protein
  • copper-transporting ATPase
  • ATPase, Cu++ transporting, beta polypeptide
  • ATP7B-like
  • ATPase, Cu(2+)-transporting, beta polypeptide
  • copper-transporting ATPase 2-like
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