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Aurora Kinase A Produkte

(Aurora Kinase A (AURKA))
The protein encoded by this gene is a cell cycle-regulated kinase that appears to be involved in microtubule formation and/or stabilization at the spindle pole during chromosome segregation. The encoded protein is found at the centrosome in interphase cells and at the spindle poles in mitosis. This gene may play a role in tumor development and progression. A processed pseudogene of this gene has been found on chromosome 1, and an unprocessed pseudogene has been found on chromosome 10. Multiple transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008].

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Ausgewählte Aurora Kinase A Kategorien

Aurora Kinase A Antikörper

High quality antibodies with extensive validation data.

Aurora Kinase A ELISA Kits

Reliable ELISA kits for a wide range of species.

Aurora Kinase A Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene Aurora Kinase A Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, IHC, ICC, FACS
Validierungen
  • (9)
Kat. Nr. ABIN5611121
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, ELISA, IF, IHC (p)
Validierungen
  • (2)
  • (5)
Kat. Nr. ABIN563053
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IF, IHC (p), ICC
Validierungen
  • (7)
Kat. Nr. ABIN2855868
Menge 100 μL
Datenblatt Datenblatt

Empfohlene Aurora Kinase A ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6965093
Menge 96 tests
Datenblatt Datenblatt

Empfohlene Aurora Kinase A Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (2)
Kat. Nr. ABIN1346206
Menge 25 μg
Datenblatt Datenblatt
Reaktivität Human
Source Escherichia coli (E. coli)
Validierungen
  • (1)
Kat. Nr. ABIN667117
Menge 50 μg
Datenblatt Datenblatt
Reaktivität Human
Source Wheat germ
Validierungen
  • (1)
Kat. Nr. ABIN1346209
Menge 10 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren Aurora Kinase A Produkten

So, Seres, Steyer, Mönnich, Clift, Pejkovska, Möbius, Schuh: "A liquid-like spindle domain promotes acentrosomal spindle assembly in mammalian oocytes." in: Science (New York, N.Y.), Vol. 364, Issue 6447, (2019) (PubMed).

Vallot, Leontiou, Cladière, El Yakoubi, Bolte, Buffin, Wassmann: "Tension-Induced Error Correction and Not Kinetochore Attachment Status Activates the SAC in an Aurora-B/C-Dependent Manner in Oocytes." in: Current biology : CB, Vol. 28, Issue 1, pp. 130-139.e3, (2018) (PubMed).

Drpic, Almeida, Aguiar, Renda, Damas, Lewin, Larkin, Khodjakov, Maiato: "Chromosome Segregation Is Biased by Kinetochore Size." in: Current biology : CB, Vol. 28, Issue 9, pp. 1344-1356.e5, (2018) (PubMed).

Kovarikova, Burkus, Rehak, Brzakova, Solc, Baran: "Aurora kinase A is essential for correct chromosome segregation in mouse zygote." in: Zygote (Cambridge, England), Vol. 24, Issue 3, pp. 326-37, (2016) (PubMed).

Flores, Castilla, Gasca, Medina, Pérez-Valderrama, Romero, Japón, Sáez: "Loss of PKCδ Induces Prostate Cancer Resistance to Paclitaxel through Activation of Wnt/β-Catenin Pathway and Mcl-1 Accumulation." in: Molecular cancer therapeutics, Vol. 15, Issue 7, pp. 1713-25, (2016) (PubMed).

Gasca, Flores, Giráldez, Ruiz-Borrego, Tortolero, Romero, Japón, Sáez: "Loss of FBXW7 and accumulation of MCL1 and PLK1 promote paclitaxel resistance in breast cancer." in: Oncotarget, (2016) (PubMed).

Casorzo, DellAglio, Sarotto, Risio: "Aurora kinase A gene copy number is associated with the malignant transformation of colorectal adenomas but not with the serrated neoplasia progression." in: Human pathology, Vol. 46, Issue 3, pp. 411-8, (2015) (PubMed).

Mahdipour, Leitoguinho, Zacarias Silva, van Tol, Stout, Rodrigues, Roelen: "TACC3 Is Important for Correct Progression of Meiosis in Bovine Oocytes." in: PLoS ONE, Vol. 10, Issue 7, pp. e0132591, (2015) (PubMed).

Premkumar, Jane, Pollack et al.: "Cucurbitacin-I inhibits Aurora kinase A, Aurora kinase B and survivin, induces defects in cell cycle progression and promotes ABT-737-induced cell death in a caspase-independent manner in malignant ..." in: Cancer biology & therapy, Vol. 16, Issue 2, pp. 233-43, (2015) (PubMed).

Hsu, Chen, Yeh, Yen, Wu, Hsu, Hsu, Chou: "TPX2 expression is associated with cell proliferation and patient outcome in esophageal squamous cell carcinoma." in: Journal of gastroenterology, Vol. 49, Issue 8, pp. 1231-40, (2014) (PubMed).

Synonyme und alternative Namen zu Aurora Kinase A

aurora kinase A (AURKA), aurora kinase A (Aurka), aurora A (aurA), aurora kinase A L homeolog (aurka.L), aurora kinase A (aurka), hypothetical protein (Aurora-A), aurora kinase A S homeolog (aurka.S), 87A7-9/2, AIK, aik, AIRK1, ARK-1, ARK1, Ark1, ark1, AU019385, Aur-A, aur-A, aur-a, AURA, AurA, aurA, aura, AURKA, aurka, aurka-a, Aurora-A, AURORA2, aurora2, AW539821, Ayk1, BTAK, btak, CG3068, ck10, ck[10], Dmel\\CG3068, Eg2, IAK, IAK1, l(3)87Ac, l(3)ck10, pEg2, PPP1R47, STK6, Stk6, stk6, STK7, stk7, STK15, stk15, wu:fb37c10, wu:fc02c02, zgc:100912

Bezeichner auf Proteinebene für Aurora Kinase A

  • ARK-1
  • Aurora-A kinase
  • IPL1-related kinase
  • aurora 2
  • aurora-related kinase 1
  • aurora/IPL1-like kinase
  • aurora/IPL1-related kinase 1
  • breast tumor-amplified kinase
  • breast-tumor-amplified kinase
  • hARK1
  • protein phosphatase 1, regulatory subunit 47
  • serine/threonine kinase 6
  • serine/threonine protein kinase 15
  • serine/threonine-protein kinase 15
  • serine/threonine-protein kinase 6
  • serine/threonine-protein kinase aurora-A
  • aurora A
  • aurora family kinase 1
  • ipl1- and aurora-related kinase 1
  • serine/threonine-protein kinase Ayk1
  • A-type aurora kinase
  • AuroraA
  • CG3068-PA
  • aur-PA
  • aurora A kinase
  • aurora kinase
  • aurora-A
  • early-A
  • fruhe2
  • ratAurA
  • serine/threonine protein kinase 6
  • Aurora A
  • aurora kinase A-A
  • p46Eg265
  • pEg2
  • serine/threonine-protein kinase 6-A
  • serine/threonine-protein kinase Eg2
  • serine/threonine-protein kinase Eg2-A
  • Aurora-A
  • Serine/threonine-protein kinase 6
  • hypothetical protein
  • aurora kinase A
  • fb37c10
  • fc02c02
  • aurora A kinase protein
  • serine/threonine-protein kinase 6-like
  • aurora kinase A-B
  • serine/threonine-protein kinase 6-B
  • serine/threonine-protein kinase Eg2-B
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