Axin Produkte
(Axin 1 (AXIN1))
Kategorien
This gene encodes a cytoplasmic protein which contains a regulation of G-protein signaling (RGS) domain and a dishevelled and axin (DIX) domain. The encoded protein interacts with adenomatosis polyposis coli, catenin beta-1, glycogen synthase kinase 3 beta, protein phosphate 2, and itself. This protein functions as a negative regulator of the wingless-type MMTV integration site family, member 1 (WNT) signaling pathway and can induce apoptosis. The crystal structure of a portion of this protein, alone and in a complex with other proteins, has been resolved. Mutations in this gene have been associated with hepatocellular carcinoma, hepatoblastomas, ovarian endometriod adenocarcinomas, and medullablastomas. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Dec 2010].
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Ausgewählte Axin Kategorien
Axin Antikörper
High quality antibodies with extensive validation data.
Axin ELISA Kits
Reliable ELISA kits for a wide range of species.
Axin Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene Axin Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Applikation
ELISA, ICC, FACS
Validierungen
- (5)
Kat. Nr.
ABIN5611198
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Rat
Applikation
WB, IHC, IP, ICC
Validierungen
- (4)
Kat. Nr.
ABIN7442327
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human
Applikation
WB, ELISA, IF, PLA
Validierungen
- (4)
Kat. Nr.
ABIN563582
Menge
100 μg
Datenblatt
Datenblatt
Empfohlene Axin ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6965097
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Competition ELISA
Validierungen
Kat. Nr.
ABIN512400
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Pig
Analytical Method
Quantitative
Validierungen
Kat. Nr.
ABIN777945
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene Axin Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
- (1)
Kat. Nr.
ABIN7121954
Menge
50 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Wheat germ
Validierungen
- (1)
Kat. Nr.
ABIN1346237
Menge
10 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
- (1)
- (1)
Kat. Nr.
ABIN2715088
Menge
20 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren Axin Produkten
: "Small-molecule binding of the axin RGS domain promotes β-catenin and Ras degradation." in: Nature chemical biology, Vol. 12, Issue 8, pp. 593-600, (2016) (PubMed).: "AHSA1 regulates proliferation, apoptosis, migration, and invasion of osteosarcoma." in: Biomedicine & pharmacotherapy, Vol. 77, pp. 45-51, (2016) (PubMed).
: "Human Sarcoma growth is sensitive to small-molecule mediated AXIN stabilization." in: PLoS ONE, Vol. 9, Issue 5, pp. e97847, (2014) (PubMed).
: "Identification and characterization of a small-molecule inhibitor of Wnt signaling in glioblastoma cells. ..." in: Molecular cancer therapeutics, Vol. 12, Issue 7, pp. 1180-9, (2013) (PubMed).
: "Differential stability of beta-catenin along the animal-vegetal axis of the sea urchin embryo mediated by dishevelled." in: Development (Cambridge, England), Vol. 131, Issue 12, pp. 2947-56, (2004) (PubMed).
: "The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation." in: Cell, Vol. 90, Issue 1, pp. 181-92, (1997) (PubMed).
Synonyme und alternative Namen zu Axin
axin 1 (AXIN1), axin 1 S homeolog (axin1.S), axin 1 L homeolog (axin1.L), axin 1 (Axin1), axin 1 (axin1), AI316800, axin, AXIN, Axin, AXIN1, AXIN1-RGS, Fu, fused, Kb, Ki, kinky, knobbly, LOC100226467, PPP1R49, wu:fi22e03, wu:fj14c08, wu:fk11b03, xAxin, zgc:109872Bezeichner auf Proteinebene für Axin
- axin 1
- axin 1, isoform 1
- axin-1-like
- axin-1
- xAxin
- axis inhibition protein 1
- axis inhibitor 1
- fused, mouse, homolog of
- protein phosphatase 1, regulatory subunit 49
- protein Fused
- GSK-3beta interacting protein rAxin
- rAxin
- masterblind
- mbl
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