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AXL Produkte

(AXL Receptor tyrosine Kinase (AXL))

Kategorien

The protein encoded by this gene is a member of the receptor tyrosine kinase subfamily. Although it is similar to other receptor tyrosine kinases, this protein represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats. It transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. It is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Ausgewählte AXL Kategorien

AXL Antikörper

High quality antibodies with extensive validation data.

AXL ELISA Kits

Reliable ELISA kits for a wide range of species.

AXL Proteine

Proteins for various applications incl. WB, ELISA, IF etc.

Empfohlene AXL Antikörper

Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Applikation WB, ELISA, RNAi
Validierungen
  • (1)
  • (6)
Kat. Nr. ABIN560017
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Applikation WB, IHC, IP, IF
Validierungen
  • (5)
Kat. Nr. ABIN7265804
Menge 100 μL
Datenblatt Datenblatt
Reaktivität Human
Applikation WB
Validierungen
  • (4)
Kat. Nr. ABIN7265803
Menge 100 μL
Datenblatt Datenblatt

Empfohlene AXL ELISA Kits

Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954023
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Rat
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (1)
Kat. Nr. ABIN6954024
Menge 96 tests
Datenblatt Datenblatt
Reaktivität Human
Analytical Method Quantitative Sandwich ELISA
Validierungen
  • (4)
  • (1)
Kat. Nr. ABIN624944
Menge 96 tests
Datenblatt Datenblatt

Empfohlene AXL Proteine

Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (5)
Kat. Nr. ABIN7273881
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Cynomolgus
Source HEK-293 Cells
Validierungen
  • (5)
Kat. Nr. ABIN7273880
Menge 100 μg
Datenblatt Datenblatt
Reaktivität Human
Source HEK-293 Cells
Validierungen
  • (4)
Kat. Nr. ABIN6961128
Menge 100 μg
Datenblatt Datenblatt

Neueste Publikationen zu unseren AXL Produkten

Novoyatleva, Rai, Kojonazarov, Veeroju, Ben-Batalla, Caruso, Shihan, Presser, Götz, Lepper, Herpel, Manaud, Perros, Gall, Ghofrani, Weissmann, Grimminger, Wharton, Wilkins, Upton, Loges, Morrell et al.: "Deficiency of Axl aggravates pulmonary arterial hypertension via BMPR2. ..." in: Communications biology, Vol. 4, Issue 1, pp. 1002, (2021) (PubMed).

Dumas, Naudin, Martin-Lannerée, Izac, Casetti, Mansier, Rousseau, Artus, Dufossée, Giese, Dubus, Pigneux, Praloran, Bidet, Villacreces, Guitart, Milpied, Kosmider, Vigon, Desplat, Dusanter-Fourt et al.: "Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5- and hypoxia- dependent up-regulation of AXL. ..." in: Haematologica, (2019) (PubMed).

Zapatero-Belinchón, Dietzel, Dolnik, Döhner, Costa, Hertel, Veselkova, Kirui, Klintworth, Manns, Pöhlmann, Pietschmann, Krey, Ciesek, Gerold, Sodeik, Becker, von Hahn: "Characterization of the Filovirus-Resistant Cell Line SH-SY5Y Reveals Redundant Role of Cell Surface Entry Factors." in: Viruses, Vol. 11, Issue 3, (2019) (PubMed).

Kasikara, Davra, Calianese, Geng, Spires, Quigley, Wichroski, Sriram, Suarez-Lopez, Yaffe, Kotenko, De Lorenzo, Birge: "Pan-TAM Tyrosine Kinase Inhibitor BMS-777607 Enhances Anti-PD-1 mAb Efficacy in a Murine Model of Triple-Negative Breast Cancer." in: Cancer research, Vol. 79, Issue 10, pp. 2669-2683, (2019) (PubMed).

Sinik, Minson, Tentler, Carrico, Bagby, Robinson, Kami, Burstyn-Cohen, Eckhardt, Wang, Frye, Earp, DeRyckere, Graham: "Inhibition of MERTK Promotes Suppression of Tumor Growth in BRAF Mutant and BRAF Wild-Type Melanoma." in: Molecular cancer therapeutics, Vol. 18, Issue 2, pp. 278-288, (2019) (PubMed).

Mills, Quinn, Roach, Palisoul, Nguyen, Noia, Guo, Fazal, Mutch, Wickline, Pan, Fuh: "p5RHH nanoparticle-mediated delivery of AXL siRNA inhibits metastasis of ovarian and uterine cancer cells in mouse xenografts." in: Scientific reports, Vol. 9, Issue 1, pp. 4762, (2019) (PubMed).

Santamaria-Barria, Zeng, Greer, Beckman, Seifert, Cohen, Zhang, Crawley, Green, Loo, Maltbaek, DeMatteo: "Csf1r or Mer inhibition delays liver regeneration via suppression of Kupffer cells." in: PLoS ONE, Vol. 14, Issue 5, pp. e0216275, (2019) (PubMed).

Jardine, Wiscombe, Reynolds, McDonald, Fuller, Green, Filby, Forrest, Ruchaud-Sparagano, Scott, Collin, Haniffa, Simpson: "Lipopolysaccharide inhalation recruits monocytes and dendritic cell subsets to the alveolar airspace." in: Nature communications, Vol. 10, Issue 1, pp. 1999, (2019) (PubMed).

Strange, Jiyarom, Pourhabibi Zarandi, Xie, Baker, Sadri-Ardekani, Shi, Verma: "Axl Promotes Zika Virus Entry and Modulates the Antiviral State of Human Sertoli Cells." in: mBio, Vol. 10, Issue 4, (2019) (PubMed).

Carestia, Mena, Olexen, Ortiz Wilczyñski, Negrotto, Errasti, Gómez, Jenne, Carrera Silva, Schattner: "Platelets Promote Macrophage Polarization toward Pro-inflammatory Phenotype and Increase Survival of Septic Mice." in: Cell reports, Vol. 28, Issue 4, pp. 896-908.e5, (2019) (PubMed).

Synonyme und alternative Namen zu AXL

AXL receptor tyrosine kinase (AXL), AXL receptor tyrosine kinase (Axl), Axl receptor tyrosine kinase (Axl), AI323647, Ark, JTK11, Tyro7, UFO, Ufo

Bezeichner auf Proteinebene für AXL

  • AXL oncogene
  • AXL transforming sequence/gene
  • tyrosine-protein kinase receptor UFO
  • adhesion-related kinase
  • ufo oncogene homolog
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