BAI1 Produkte
(Brain-Specific Angiogenesis Inhibitor 1 (BAI1))
Kategorien
Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008].
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Ausgewählte BAI1 Kategorien
BAI1 Antikörper
High quality antibodies with extensive validation data.
BAI1 ELISA Kits
Reliable ELISA kits for a wide range of species.
BAI1 Proteine
Proteins for various applications incl. WB, ELISA, IF etc.
Empfohlene BAI1 Antikörper
Produkt
Reaktivität
Applikation
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human, Mouse
Applikation
WB, IHC (p), FACS
Validierungen
- (4)
Kat. Nr.
ABIN392804
Menge
400 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
WB
Validierungen
- (3)
Kat. Nr.
ABIN3181614
Menge
100 μL
Datenblatt
Datenblatt
Reaktivität
Human, Mouse, Rat
Applikation
IHC, WB, ELISA, IF, ICC
Validierungen
- (3)
Kat. Nr.
ABIN6257957
Menge
100 μL
Datenblatt
Datenblatt
Empfohlene BAI1 ELISA Kits
Produkt
Reaktivität
Analytical Method
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
- (1)
Kat. Nr.
ABIN6954184
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN4881934
Menge
96 tests
Datenblatt
Datenblatt
Reaktivität
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validierungen
Kat. Nr.
ABIN6385397
Menge
96 tests
Datenblatt
Datenblatt
Empfohlene BAI1 Proteine
Produkt
Reaktivität
Source
Validierungen
Kat. Nr.
Menge
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN7413106
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
HEK-293 Cells
Validierungen
Kat. Nr.
ABIN6964229
Menge
100 μg
Datenblatt
Datenblatt
Reaktivität
Human
Source
Escherichia coli (E. coli)
Validierungen
Kat. Nr.
ABIN6121439
Menge
100 μg
Datenblatt
Datenblatt
Neueste Publikationen zu unseren BAI1 Produkten
: "BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation." in: Cancer cell, Vol. 33, Issue 6, pp. 1004-1016.e5, (2018) (PubMed).: "Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion." in: Nature, Vol. 497, Issue 7448, pp. 263-7, (2013) (PubMed).
: "Antiangiogenic activity of BAI1 in vivo: implications for gene therapy of human glioblastomas." in: Cancer gene therapy, Vol. 13, Issue 4, pp. 385-92, (2006) (PubMed).
: "Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression." in: The American journal of pathology, Vol. 162, Issue 1, pp. 19-27, (2002) (PubMed).
: "Overexpression of the p53-inducible brain-specific angiogenesis inhibitor 1 suppresses efficiently tumour angiogenesis." in: British journal of cancer, Vol. 86, Issue 3, pp. 490-6, (2002) (PubMed).
: "Brain-specific angiogenesis inhibitor 1 (BAI1) is expressed in human cerebral neuronal cells." in: Neuroscience research, Vol. 43, Issue 1, pp. 69-74, (2002) (PubMed).
Synonyme und alternative Namen zu BAI1
brain-specific angiogenesis inhibitor 1 (BAI1), adhesion G protein-coupled receptor B1 (ADGRB1), brain-specific angiogenesis inhibitor 1 (LOC100228084), adhesion G protein-coupled receptor B1 (Adgrb1), B830018M07Rik, BAI1, GDAIF, mKIAA4089, R75078Bezeichner auf Proteinebene für BAI1
- brain-specific angiogenesis inhibitor 1
- brain-specific angiogenesis inhibitor 1-like
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